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Alternative Therapy for Depression?; FDA Actions
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Thirty-three of the more than 3000 lost boys of Sudan (mean age, 25 years) in the United States were evaluated. All but 6 reported chronic abdominal pain. Ten (48%) of 21 had Schistosoma mansoni and one had S. haematobium infection, while 5 (20%) of 25 were HBsAg carriers and 3 (12%) of 25 had chronic hepatitis due to HBV.
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This paper reports on 5 HIV-infected patients receiving TDF-containing antiretroviral (ARV) therapy who developed ARF. One patient had associated Fanconi syndrome/renal tubular acidosis (RTA).
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When Primary Ebstein-Barr Infection occurs in early childhood, it is usually asymptomatic. Infection later, during adolescence or in adulthood, is associated with a classic syndrome that we term infectious mononucleosis (IM), mono in the vernacular.
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Bacterial resistance to antibiotic treatment has concerned the medical community since the introduction of the first antibiotics in the 1920s. Development of new anti-infective agents has been precipitated by increasing resistance to older agents and classes of agents. While high rates of resistant organisms have been particularly problematic in hospital intensive care units, serious resistance now is being encountered in community-acquired infections. This review will focus on the clinical aspects of antibiotic resistance in community-acquired respiratory infections, pharyngitis, skin infections, and urinary tract infections.
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Each year in the United States, a few isolated cases of plague are reported. This year, possibly because of increased spring rains leading to an increase in the rodent population, an unprecedented 13 cases of plagues have occurred in 4 states (New Mexico, California, Colorado, and Texas).
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A prospective study of the immunogenicity and reactogenicity of one vs 2 doses of 2004-2005 trivalent influenza vaccine (TIV), in 5 8-year-old children, was conducted among 280 children who had not received TIV. Of these, 222 received 2 doses of TIV and had 3 blood samples. An additional 10 received 2 doses of TIV and were included in the safety analyses. The mean age of the 222 children was 6.5 years; 57% were male.
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From July through November 2003, a rapidly growing non-tuberculous Mycobacterium was recovered in culture from 11 of 15 women with wound infections after breast surgery all but one involving silicon gel implants. Thirteen of the procedures were performed by a single surgeon; infection developed in 12 of 42 (28.6%) patients operated on by this individual.
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The optimal time to initiate antiretroviral therapy (ARV) in chronically-infected asymptomatic patients is now felt to be when the CD4+ lymphocyte count falls to approximately 350 cells/uL, based on the probability of developing an AIDS-defining illness within a relatively short period of time, as shown in a meta-analysis of cohort studies.
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