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Infectious Disease

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  • Full February 15, 2006 issue in PDF

  • ECG Review: A 73-Year-Old Man with Dyspnea

    The 12-lead ECG in the Figure was obtained from a 73-year-old man with dyspnea. What ECG findings do you see that may account for his symptoms?
  • Clinical Briefs By Louis Kuritzky, MD

    Efficacy and Safety of Benazepril for Advanced Chronic Renal Insufficiency; Prognostic Value of Thyroid Hormone Levels in Acute MI: Just an Epiphenomenon?; Nonsteroidal Anti-inflammatory Drugs and the Risk of Actinic Keratoses and Squamous Cell Cancers of the Skin
  • Pharmacology Update: Conivaptan Injection (Vaprisol®)

    The FDA has approved the first of a new class of agents, the vaptans. Conivaptan, the first arginine vasopressin receptor antagonist, is approved for the management of serious sodium/water imbalance. It will be marketed by Astellas Pharma US, Inc as Vaprisol®.
  • Forgotten Hazards of Sedatives

    This case series and prospective observational study describe propylene glycol toxicity in patients receiving IV benzodiazepines. The authors estimate the incidence of this important but unrecognized complication to be 19%.
  • Is LDL Cholesterol the Best CHD Lipid Marker?

    Illnesses produced by vascular diseases are far and away the most common cause of death in the developed world and, amazingly enough, will become the leading cause of death even in the developing world by 2020.1 Identifying individuals at increased risk of coronary artery heart disease (CHD) is critical in preventing CHD and, in 2002, the Adult Treatment Panel III (ATP III)2 reaffirmed its previous position by concluding that low-density lipoprotein cholesterol (LDL-C) would remain the cornerstone of lipid management.
  • Shaky Evidence for an Old Technique

    The use of a steroid ointment following a 20-minute soak may relieve chronic skin conditions.
  • Napoleon, Typhus, and Trench Fever

    In the autumn of 2001, construction workers in the Siaures Miestalis (Northern Town) section of Vilnius uncovered a mass grave containing several thousand neatly stacked skeletons, most in a fetal position.
  • Diabetic Foot Infections: Culture Results from Bone Biopsy and Swab Specimens

    This study from a single diabetic foot clinic in France involved a retrospective chart review of patients who underwent surgical percutaneous bone biopsy with culture for microbiologic diagnosis of osteomyelitis. Patients included for study were those who had not received either local or systemic antibiotics for at least 4 weeks prior to cultures being obtained.
  • Update on Moxifloxacin (Avelox): New Indications

    Since the fda approval of moxifloxacin in December 1991 for the treatment of community-acquired pneumonia, sinusitis, acute bacterial exacerbation of chronic bronchitis, and uncomplicated skin/skin structure infections, its indications for use has been expanded to include the treatment of complicated skin/skin structure infections and complicated intra-abdominal infections.