Infectious Disease
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COVID-19 Vaccine mRNA Suspension for Injection (Comirnaty, Spikevax)
The Food and Drug Administration has approved and granted emergency use authorization for updated messenger ribonucleic acid (mRNA) COVID-19 vaccines.
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Out of Africa Again? A New Version of Mpox
A novel mpox clade has emerged in Africa and has the potential for a global epidemic.
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Infectious Disease Updates
Managing Neurosyphilis; Combatting the Resurgence of Syphilis
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Does Semaglutide Protect Against Adverse Effects from COVID-19?
Semaglutide recipients who developed COVID-19 had significant protection against the occurrence of adverse outcomes, including death.
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Twice-Yearly Subcutaneous Lenacapavir Injection Prevents HIV Infection
Subcutaneous injection of lenacapavir every 26 weeks had 100% efficacy in preventing human immunodeficiency virus (HIV) infection in a high-risk population.
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Viruses, Newborns, and Liver Failure
Neonatal liver failure due to herpesvirus infection is rare but can be severe. Herpes simplex virus 1 (HSV-1) is a more likely cause than HSV-2. Only about two-thirds of affected patients survive, despite recommended treatment with parenteral acyclovir.
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Metformin Reduces SARS-CoV-2 Viral Load in Outpatients with COVID-19
A randomized, placebo-controlled clinical trial of outpatients with COVID-19 found that metformin reduced SARS-CoV-2 viral load 3.6-fold compared to placebo, while ivermectin and fluvoxamine showed no benefit.
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The Rise of Oropouche Virus
Oropouche virus is an arthropod-borne virus that has been primarily endemic to the Amazon region. The incidence of Oropouche virus disease has significantly increased over the past few years, and recent outbreaks have been reported in areas without previous endemic transmission and have led to fatalities and vertical transmission resulting in adverse pregnancy outcomes.
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Enlargement of Choroid Plexus in Subacute COVID-19 Patients
The choroid plexus is a network of capillaries whose main role involves facilitating cerebrospinal fluid production and the exchange of nutrients and waste products between the central nervous system and the bloodstream. Immune cells are present near the choroid plexus. Enlargement of the choroid plexus has been noted in patients with multiple sclerosis.
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Infectious Disease Alert Updates
Abandoning Universal COVID Admission Screening; Does Obesity Affect HIV Drug Levels? Eat Your Fruits and Vegetables!