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Exposure to coccidioidomycosis in the laboratory can represent a significant hazard, resulting in serious and even fatal infection. In particular, opening culture plates in the lab, without appropriate precautions, can result in the aerosolization of artificially large numbers of arthroconodia.
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In this issue: Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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Twice in the past 2 years I've encountered pulmonary histoplasmosis in travelers returning from Central America (Mexico and Costa Rica), and both times the diagnosis proved challenging. One case, in particular, was a 60-year-old man who had traveled to Costa Rica for 1 week and then presented with fever, persistent dry cough, malaise, and complaints of memory loss.
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Herpes zoster vaccine (Zostavax) was licensed in the United States in 2006 subsequent to the publication of the Shingles Prevention Study, a large (n = 38,546) prospective trial that demonstrated a 51% reduction in zoster and a 67% reduction in postherpetic neuralgia in vaccines compared to controls.
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Leptospirosis is a zoonosis caused by multiple serovars of bacteria in the genus Leptospira that are widely distributed in the tropics, as well as some subtropical and temperate areas.
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Admissions to a public hospital in kwazulu-natal, South Africa, for treatment of MDR- and XDR-TB from 2003 to 2008 were examined for health care workers (HCWs) compared with non-HCWs.
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In this issue: Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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In this meta-analysis, individuals who exercised or had sex episodically had an increased risk of acute cardiac events during those activities compared with those who had high levels of habitual physical activity.
