For many patients with moderate- severe chronic obstructive pulmonary disease, acute exacerbations (AECOPD) are highly problematic.
In nonvalvular atrial fibrillation patients, rivaroxaban was noninferior to warfarin for the prevention of stroke or systemic embolism. However, an intention-to-treat analysis did not show superiority of rivaroxaban over warfarin.
It has been well recognized that a peak in stroke onset occurs during the early morning hours. This possible circadian periodicity is not well understood, and may in part represent stroke onset earlier during the night that goes unrecognized until the patient arouses.
Sickle cell disease celebrated its 100th anniversary last year, prompting consideration of what has transpired for those with the disease since its description by Dr. James Herrick in 1910.
A descriptive study enrolled children 2-18 years of age presenting to a pediatric emergency department in Rhode Island during the months of April through December of 2006-2009.
Clinical laboratories in north america are increasingly switching to the newer treponemal-specific assays, such as the enzyme immunoassay (EIA) or chemiluminescence immunoassay (CIA) for syphilis testing.
Xigris® (drotrecogin alfa [activated]), a recombinant form of human activated protein C, received FDA approval in November 2001 for the reduction of mortality in adult patients with severe sepsis with a high risk of death.
Congenital toxoplasmosis occurs exclusively in infants born to mothers who acquire primary infection during their pregnancy. Unfortunately, many of these infections occur without clinical signs or symptoms, and the mothers go untreated.
A descriptive study enrolled children 2-18 years of age presenting to a pediatric emergency department in Rhode Island during the months of April through December of 2006-2009. Children were enrolled who had pleocytosis, defined as white blood cell count of > 8/mm3 in the cerebrospinal fluid (CSF), in the absence erythema migrans rash, cranial neuropathy, papilledema, a positive Gram stain, antibiotic use within 2 weeks, chronic
