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A descriptive study enrolled children 2-18 years of age presenting to a pediatric emergency department in Rhode Island during the months of April through December of 2006-2009. Children were enrolled who had pleocytosis, defined as white blood cell count of > 8/mm3 in the cerebrospinal fluid (CSF), in the absence erythema migrans rash, cranial neuropathy, papilledema, a positive Gram stain, antibiotic use within 2 weeks, chronic
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Congenital toxoplasmosis occurs exclusively in infants born to mothers who acquire primary infection during their pregnancy. Unfortunately, many of these infections occur without clinical signs or symptoms, and the mothers go untreated.
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Xigris® (drotrecogin alfa [activated]), a recombinant form of human activated protein C, received FDA approval in November 2001 for the reduction of mortality in adult patients with severe sepsis with a high risk of death.
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The FDA has approved the first fixed-dose combination product for the treatment of type 2 diabetes and hypercholesterolemia. This tablet combines a dipeptidyl peptidase-4 inhibitor (sitagliptin) and a HMG-CoA reductase inhibitor (simvastatin).
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In a large randomized trial of healthy men, dietary supplementation with vitamin E (400 IU/day) significantly increased the risk of prostate cancer.
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In a large community-based cohort of older women, those who self-reported use of multivitamins, vitamin B6, folate, iron, magnesium, zinc, and copper were more likely to die than those who do not. Calcium use, however, was associated with reduced risk.
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The presence of any observed hostility at baseline was associated with a two-fold increased risk of incident ischemic heart disease over a 10-year period of observation.
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The lead II rhythm strip shown above was obtained from a woman with new-onset palpitations. How would you interpret this tracing? How certain are you of your answer? Clinically what would you do?
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The decode data (diabetes epidemiology Collaborative Analysis of Diagnostic Criteria in Europe) indicated that all-cause mortality, as well as cardiovascular (CV) events, were better predicted by postprandial glucose (PPG) than fasting blood glucose (FPG).