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Infectious Disease

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  • Rectal Colonizing E. coli Cause Most Infections Following Transrectal Biopsy of the Prostate

    An observational cohort study found that rectal colonizing strains of E. coli are the source for most fluoroquinolone-resistant post-transrectal prostate biopsy infections. Pre-procedure screening cultures should be considered.

  • The Response to Ebola in the United States — Current Status and Lessons Learned

    Much was learned in the United States in dealing with the fear of Ebola virus infection — but can we avoid wasteful panic with the next outbreak of a novel pathogen?

  • Clinical Briefs

    Clinical Briefs on topics such as: Chronobiology and Insulin Glargine, Dual Add-on Therapy for Type 2 Diabetes When Metformin is Not Enough, and Might Long-term Dual Antiplatelet Therapy Be Better? Not

  • Are Atrial Premature Complexes Benign?

    Atrial premature complexes (APCs) are commonly observed on routine ECGs and believed to be harbingers of atrial fibrillation, especially in patients with cardiovascular disease. However, little is known about the long-term prognosis of APCs in the general population. Thus, these investigators from Japan analyzed the database of a large community-based cohort from 1993 to 2008 to determine the risks of APCs seen on the subjects’ baseline ECGs.

  • Statins After an MI: Does it Happen?

    Following a hospitalization for coronary heart disease (CHD) or acute coronary syndrome (ACS), randomized trials demonstrate that high-intensity atorvastatin is more effective than either placebo or low- to moderate-intensity therapy with either pravastatin or atorvastatin.1-3 Based on this evidence, the American College of Cardiology and the American Heart Association guidelines recommend high-intensity therapy in cases of an acute cardiac event and that therapy be initiated before discharge.

  • Is it Worth it? Do “Healthy” Dietary Guidelines Lower the Risk of Heart Disease?

    Recent controversy surrounds diet and its impact on cardiovascular disease (CVD). In this study, Reidlinger and her colleagues sought to assess diet by comparing the effects on vascular and lipid CVD risk factors of adhering to a diet consistent with United Kingdom (UK) dietary guidelines (DG group) to a traditional British diet (control group).

  • Another Reason to Recommend Smoking Cessation

    Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, affecting an estimated 2.7 million individuals in the United States.1 The proportion of strokes attributable to AF increases strikingly from 1.5% at 50-59 years of age to 23.5% at 80-89 years of age.2 Approximately 15-20% of all strokes are due to AF. To predict the thromboembolic risk in the individual patient, risk models used most frequently are CHA2DS2-VASc and CHADS2 scores. The CHA2DS2-VASc score may be the better option since both the 2014 American Heart Association, American College of Cardiology, Heart Rhythm Society AF guidelines, and the 2012 European Society of Cardiology AF guidelines prefer it when evaluating the individual thromboembolic risk associated with AF and to determine the risk:benefit ratio of antithrombotic therapy.3

  • Culturing protocols devised for duodenoscopes to prevent CRE

    Responding to a series of outbreaks of carbapenem-resistant Enterobacteriaceae (CRE) linked to duodenoscopes, the Centers for Disease Control and Prevention has developed an interim protocol for culturing the devices before use to create a greater margin of safety for patients. But as others have noted, the approach is not foolproof and could be costly if facilities determine that they must purchase more scopes to adopt the protocol.

  • CDC: Only one confirmed occupational HIV infection in a U.S. health care worker since 2000

    In the 1980s when HIV infection was tantamount to a death sentence, health care workers bravely took care of the first epidemic waves of AIDs patients.

  • Hospital goes high tech, improves hand hygiene

    An Alabama hospital greatly improved hand hygiene compliance and significantly reduced health care associated infections (HAIs) after installing an automated hand-hygiene monitoring system.