Infectious Disease
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Preventing Active Tuberculosis in Children
A three-month course of weekly rifapentine and isoniazid is safe and at least as effective as nine months of daily isoniazid in preventing tuberculosis in children aged 2 to 17 years.
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Steroids for Severe Community-Acquired Pneumonia: More Evidence or More Uncertainty?
A multicenter, randomized, double-blind, placebo-controlled trial involving patients with severe community-acquired pneumonia and evidence of high inflammation found less treatment failure in those who received steroids. However, in-hospital mortality did not differ between the groups.
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Acute Leukemia Patients Still Plagued by Vancomycin-Resistant Enterococci
Fifteen (7%) of 214 patients hospitalized with newly diagnosed acute leukemia developed bacteremia due to vancomycin-resistant enterococci; 12 (80%) of the 15 had stool colonization with the organism.
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Fusobacterium as a Cause of Pharyngitis in Young Adults
Three hundred twelve students presenting to a university student health clinic with sore throat and 180 asymptomatic students had throat swabs taken and the samples were tested by PCR for Fusobacterium necrophorum, Mycoplasma pneumonia, group A streptococci, and group C/G streptococci. Fusobacterium necrophorum-positive pharyngitis occurs more frequently than group A streptococcal pharyngitis in this population and clinically resembles streptococcal pharyngitis.
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Seizures, Encephalopathy, and Vaccines — Evidence Fails to Support a Link
A comprehensive, independent review of 10 years of all cases in the United States of seizures and encephalopathy reported as linked to vaccination showed that approximately one-quarter of cases had evidence of a pre-existing neurologic abnormality. Among those who developed chronic epilepsy, many had clinical features suggesting genetically determined epilepsy, especially Dravet syndrome.
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Nurse: Hospital lied, tricked her for PR benefit
One of the more shocking allegations in the lawsuit nurse Nina Pham filed recently against Texas Health Presbyterian Hospital Dallas involves what she says was a deceitful attempt to help bolster the hospital’s public image during a frenzy of media coverage about Ebola.
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Ebola lawsuit claims nurse was thrust into danger without proper training
The Kafkaesque story told in the lawsuit filed by nurse Nina Pham features a woman who innocently shows up for work one day and finds herself trapped in a nightmare, betrayed by those she trusted to protect her.
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Harsh claims as nurse sues hospital where she contracted Ebola
A nurse who contracted Ebola after treating a patient with the disease is suing her hospital. She claims the hospital failed to provide adequate training and protective gear, among several other charges. The nurse says she still suffers physically and mentally from the experience. She alleges that the hospital used her for public relations efforts against her will.
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Clinical Briefs
Modifying the Home Environment to Prevent Falls
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Secukinumab Injection (Cosentyx™)
A recombinant, fully humanized monoclonal antibody to interleukin-17 has been approved for the treatment of moderate-to-severe plaque psoriasis. Secukinumab is marketed by Novartis as Cosentyx.