Infectious Disease
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Lower nurse-patient ratios could cut infections, but hospitals say mandates could crash budgets
A flurry of state and national efforts to mandate safer nurse-to-patient ratios in healthcare could result in both lower infection rates and improved employee health. -
Researchers find norovirus may spread by airborne route, are current precautions enough?
Nasty bug norovirus may transmit through the air, meaning currently recommended infection precautions may not be enough -
What’s in your water? Waterborne bugs can cause fatal infections
The water of life can sometimes mean death. Fatal infections can result if immune compromised patients are exposed to pathogenic bacteria that thrive in water systems. -
Ivabradine Tablets (Corlanor ®)
Ivabradine's effect in reducing heart rate, by acting on the SA node, was most prominent at a higher heart rate, thus minimizing the risk of bradycardia.
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Clindamycin vs. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Infections
Cure rates did not differ between the treatments and rates of adverse events were similar in the two groups.
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Utility of the New Cholesterol Guidelines
The risk:benefit ratio is much better for moderate- than high-intensity statins.
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Risk of NSAID Use in Patients Receiving Antithrombotic Therapy After Myocardial Infarction
The use of NSAIDs was associated with increased risk of bleeding and excess thrombotic events, even after short-term treatment.
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Treatment of Invasive Aspergillosis: Are Two Drugs Better Than One?
Although potential benefit may have been detected in a post hoc subset analysis, the addition of anidulafungin in the initial phase of primary treatment of suspected or documented invasive aspergillosis was not associated with a significant improvement in survival.
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Nasal Screening for MRSA: The New Basis for De-escalation of Empiric Antibiotics?
The high negative predictive value of a negative nasal screen for methicillin-resistant Staphylococcus aureus suggests these patients do not have lower respiratory tract infections caused by the organism.
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Initial Antiretroviral Regimens — New Recommendations
Four of the five recommended initial antiretroviral regimens in treatment-naïve adolescents and adults are based on integrase strand transfer inhibitors.