Infectious Disease
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D-Day: Unprecedented national plan aims to save the antibiotic era
Antibiotic stewardship to rein in the rampant misuse and overuse of drugs is a national priority involving the highest levels of the federal government.
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Infectious Disease Alert Updates
Legionella Revisited; Treatment of Latent Tuberculosis; Transmission of Clostridium difficile from Asymptomatic Carriers
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Caring for Unaccompanied Central American Immigrant Children
Physicians can improve the health of unaccompanied Central American immigrant children by ensuring appropriate vaccination, by identifying culturally and linguistically appropriate community resources, and by becoming involved in patient advocacy.
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Pneumonia in U.S. Children Requiring Hospitalization
Two thousand six hundred thirty-eight children with a clinical diagnosis of community-acquired pneumonia (CAP) were enrolled in a prospective surveillance study. Eighty-nine percent had radiographic evidence of pneumonia. The median age of children hospitalized was 2 years, with the highest rates seen in children younger than 2 years. Respiratory viruses were the most commonly detected pathogens.
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Typhoid Vaccination
Vaccination against typhoid continues to be important for many travelers to at-risk countries in Asia, Africa, and Latin America.
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Rectal Colonizing E. coli Cause Most Infections Following Transrectal Biopsy of the Prostate
An observational cohort study found that rectal colonizing strains of E. coli are the source for most fluoroquinolone-resistant post-transrectal prostate biopsy infections. Pre-procedure screening cultures should be considered.
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The Response to Ebola in the United States — Current Status and Lessons Learned
Much was learned in the United States in dealing with the fear of Ebola virus infection — but can we avoid wasteful panic with the next outbreak of a novel pathogen?
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Clinical Briefs
Clinical Briefs on topics such as: Chronobiology and Insulin Glargine, Dual Add-on Therapy for Type 2 Diabetes When Metformin is Not Enough, and Might Long-term Dual Antiplatelet Therapy Be Better? Not
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Are Atrial Premature Complexes Benign?
Atrial premature complexes (APCs) are commonly observed on routine ECGs and believed to be harbingers of atrial fibrillation, especially in patients with cardiovascular disease. However, little is known about the long-term prognosis of APCs in the general population. Thus, these investigators from Japan analyzed the database of a large community-based cohort from 1993 to 2008 to determine the risks of APCs seen on the subjects’ baseline ECGs.
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Statins After an MI: Does it Happen?
Following a hospitalization for coronary heart disease (CHD) or acute coronary syndrome (ACS), randomized trials demonstrate that high-intensity atorvastatin is more effective than either placebo or low- to moderate-intensity therapy with either pravastatin or atorvastatin.1-3 Based on this evidence, the American College of Cardiology and the American Heart Association guidelines recommend high-intensity therapy in cases of an acute cardiac event and that therapy be initiated before discharge.