Infectious Disease
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Decreasing Cross-Transmission of Carbapenemase-Producing Enterobacteriaceae
A bundled infection control intervention was shown to decrease cross-colonization, prevalence, and bloodstream infection of Klebsiella pneumonia carbapenemase-producing Enterobacteriaceae in long-term acute care hospitals, which may have far-reaching effects into the ICU.
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When Profiling Is a Good Thing: Distinguishing Bacterial from Viral Infection
Transcriptional analysis outperformed serum procalcitonin in distinguishing viral from bacterial infections.
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Does Bacteremia Associated with Bone and Joint Infections Require Prolonged IV Antibiotic Therapy?
Two hundred sixty-five children with culture-proven acute bone or joint infections were studied. All patients received 2-4 days of IV antibiotics followed by PO antibiotics. Clinical outcomes and resolution of inflammatory biomarkers were the same whether the patient had positive blood cultures or not on admission.
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BCG — Back to the Future?
In a population-based study, neonatal vaccination with bacille Calmette-Guérin significantly reduced rates of hospitalization for non-tuberculous respiratory infection and sepsis. BCG vaccine might provide significant protection through nonspecific immune enhancement.
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Polio — New Strategies as We Get Close to Eradication
The switch to a bivalent live attenuated oral polio vaccine by elimination of serotype 2 will be coordinated with the use of trivalent inactivated vaccine. The goal is to eliminate outbreaks of polio due to vaccine serotype 2, the major cause of such events.
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Antibiotics for Acute Appendicitis
ABSTRACT & COMMENTARY: Of those who needed surgery after treatment with antibiotics, the risk for complications was low.
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Clostridium difficile causing some 8,700 fatal infections in long-term care annually
C. diff is becoming a leading killer in nursing homes, as residents predisposed to the brutal infection by antibiotic treatments in both hospitals and long-term care settings succumb to this opportunistic gut dweller.
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APIC looks to frame the future, empower IP
At risk of being overwhelmed by data collection demands, infection preventionists are also arguably at their highest profile in the field’s history in a time of Ebola, MERS, and the threat of other emerging infections and pandemics. Real reductions in healthcare infections once considered inevitable are proving possible for those that can find the time and resources to intervene and implement prevention strategies. For today’s IP, the opposite poles are the infamous silo and the patient bedside.
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With TB at a record low in U.S., OSHA ramps up inspections in healthcare
OSHA — which lost an epic battle with the infection control community to adopt a separate tuberculosis standard more than a decade ago — has decided to put TB back on its radar and update compliance requirements for healthcare settings.
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A 58% mortality rate: 509 healthcare workers have died in Ebola outbreak in West Africa
During the historic Ebola outbreak in West Africa that is now making its last stand, 509 healthcare workers gave their lives trying to save others. The deaths translate to a mortality rate of 58% of the 875 healthcare workers infected as of July 5, 2015, the WHO reports.