Infectious Disease
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Sacubitril and Valsartan Tablets (Entresto)
A new option for heart failure incorporates two drugs with different mechanisms of action.
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Antibiotics for Acute Appendicitis
A randomized, multicenter clinical trial compared antibiotic therapy to surgery for uncomplicated acute appendicitis and found most patients who received antibiotics did not require appendectomy during the 1-year follow-up period.
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Are Premature Ventricular Contractions Dangerous?
A higher frequency of premature ventricular contractions was associated with a decrease in left ventricular ejection fraction, an increase in incident congestive heart failure, and an increase in mortality.
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The Spice of (Prolonged) Life
ABSTRACT & COMMENTARY: Habitual consumption of spicy foods is associated with reduced mortality independent of other risk factors for death. Hot stuff!
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Infectious Disease Alert Updates
TB Screening for High-Tech Workers
Cellulitis or Pseudocellulitis?
Screening for Creutzfeldt-Jakob Disease Before Invasive Procedures
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Influenza Vaccination: Updated Information for 2015-16
The CDC has published updates of last year’s recommendations of the Advisory Committee on Immunization Practices for the use of seasonal influenza vaccines. The following is a selection of some of the most pertinent ones.
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Scrub Typhus and the Brain
Scrub typhus infections involve the nervous system in a majority of cases and should be suspected in patients who live in, or are returning from, endemic regions with a compatible clinical syndrome.
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“Only Skin Deep” — Preventing and Managing Dermatologic Problems in Travelers
Skin infections and infestations account for significant concern among returned travelers. Appropriate diagnosis and treatment makes long-term morbidity unlikely.
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Risk of Herpes Zoster Increases After Zoster Vaccination in Patients Taking Immunosuppressive Medications
In adults >18 years, taking immunosuppressive medications at the time of zoster vaccination increased the risk for herpes zoster for up to 6 weeks afterward (adjusted odds ratio, 2.99; 95% CI, 1.58-5.70).
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Legionella in the Bronx
On July 30, 2015, The New York Times reported that the New York City Department of Public Health was investigating an outbreak of Legionnaire’s disease in the South Bronx.