Infectious Disease
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CDC Warning: Enterovirus-D68 Re-Emerging and Once Again Raising the Specter of Acute Flaccid Myelitis in Children
The Centers for Disease Control and Prevention is receiving increasing reports of pediatric infections with enterovirus-D68, which previously has been associated with the development of acute flaccid myelitis.
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Safety of Infliximab After Live Vaccines
Despite concerns about the use of infliximab for children with Kawasaki disease shortly after administration of live vaccines, retrospective reviews do not show any vaccine-related infections following subsequent infliximab use.
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Doxycycline Plus a Beta-Lactam for Treatment of Inpatients with Community-Acquired Pneumonia
In this retrospective study of an elderly male population hospitalized with community-acquired pneumonia, the combination of doxycycline with a beta-lactam was at least as effective as a respiratory fluoroquinolone or a combination of a beta-lactam with azithromycin.
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Cellular Tests Are Not Accurate for Diagnosing Lyme Disease
A prospective case-control study from the Netherlands evaluated three cellular tests for diagnosing Lyme disease. All three had low specificity compared to serological testing, leading to an unacceptably high number of false-positive results.
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Boosting with the New Bivalent COVID-19 Vaccines
The Centers for Disease Control and Prevention has made recommendations for the use of the newly approved bivalent COVID-19 booster vaccine.
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Antibiotic Resistance: We Were Doing Great and then COVID Happened
After improvement, antimicrobial resistance in the United States significantly increased.
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Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD
This multicenter cohort study revealed a high incidence of PTSD symptoms among family members of COVID-19 patients at three months after the ICU admission.
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Remaining Questions in Syphilis Treatment
Eight leading experts on sexually transmitted diseases convened to discuss key questions in the management of syphilis in adults with and without HIV infection based on a systematic review of the literature. More than 3,000 articles were screened, and the discussion focused on 95 relevant publications and three main topics.
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Smallpox and Monkeypox Vaccine, Live, Non-Replicating (Jynneos)
Jynneos can be administered to prevent smallpox and monkeypox in adults age 18 years and older who are at high risk for contracting the infections.
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Cirrhosis and Infections
Infections in patients with cirrhosis are frequent and potentially lethal, with pneumonia associated with the highest risk for mortality.