Infectious Disease
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Hospital-acquired Infections and Other Hospital-acquired Conditions — How Are We Doing?
There was a large decrease in the number of total hospital-acquired conditions from 2010-2014, but with no improvement from 2013-2014. While there were decreases in hospital-acquired infections, much further improvement is needed.
Clinical Briefs
In this section: no payoff to physical therapy after healed ankle fracture; bisphosphonates and bone recurrence; and manipulating the microbiome.
No More Bacon? Carcinogenicity of Meat
A review of published research by the World Health Organization concludes that processed meats are probably carcinogenic.
Naloxone Nasal Spray (Narcan)
The FDA has approved naloxone in the form of a nasal spray as a life-saving medication to reverse the effects of an opioid overdose.
Nicotinamide Chemoprevention for Skin Cancer Is Impressive
In a Phase III, double-blind, randomized, placebo-controlled trial, oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients.
Vitamin D Levels and Cognitive Function: Does It Make a Difference?
Similar to previous studies, vitamin D deficiency and insufficiency rates were not significantly different between those with normal cognitive status, mild cognitive impairment, or dementia. However, cognitive decline occurred at a significantly greater rate in individuals with low 25-hydroxyvitamin D levels in the areas of episodic memory and executive function.
Is it Normal Aging or Chronic Kidney Disease?
Current clinical guidelines for the diagnosis of chronic kidney disease resulted in more than half of adults > 70 years of age having chronic kidney disease. Should these guidelines change to require age calibration for diagnosis and classification of chronic kidney disease?
ECG Review: Why are aVR Waveforms Positive?
Clinical Briefs
In this section: Are annual physicals worth it?; breakfast might be the most important meal of the day; and evaluating the total knee replacement.Insulin Degludec Injection (Tresiba)
Insulin degludec provides an alternative to insulin glargine and insulin detemir as long-acting human insulin analogs.