Infectious Disease
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Saccharomyces Cerevisiae var boulardii ( S. boulardii ) and Antibiotic-associated Diarrhea
Saccharomyces boulardii administration failed to prevent antibiotic-associated diarrhea in a large randomized trial.
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Antibiotic Use in Treatment of Children with Uncomplicated Severe Acute Malnutrition
Universal antibiotic use in the community-based treatment of uncomplicated severe acute malnutrition in children likely is not necessary in regions where suitable access to healthcare facilities is available.
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Pediatric Coccidioidomycosis in California, 2000-2012
The incidence of pediatric coccidioidomycosis in California has increased significantly from 2000 until 2012, along with hospitalization for complicated disease. Latino children were most commonly infected, but African-American children were significantly more likely to be hospitalized.
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Trimethoprim-sulfamethoxazole versus Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized clinical trial found that a 7-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo (80.5% vs 73.6%, respectively; P = 0.005).
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Global Village: After Ebola and Zika, Patient Admitted to U.S. Hospital with Lassa Fever
As this issue went to press, the CDC confirmed that a patient admitted to Emory University Hospital’s Serious Communicable Diseases Unit has Lassa fever, a hemorrhagic virus endemic in parts of West Africa.
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Zika Update: U.S. Approaching 200 Cases
As confirmed cases of the Zika virus disease continue to mount in the United States, frontline providers are scrambling to ensure that appropriate patients are screened for the illness, and to minimize the risk of transmission, especially to pregnant women.
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Increasing Job Requirements Warrant More Funding for IPs, Epidemiologists
As infection prevention and healthcare epidemiology continue to undergo a dramatic transformation in duties and responsibilities, resources and program support are lagging in many hospitals even as a Zika virus outbreak follows closely on the heels of Ebola.
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The One and the Many: Experts Urge New Paradigm on Antibiotic Resistance
While the widespread overuse and misuse of antibiotics is frequently cited in discussions of increasing bacterial resistance, there are instances where even correct use for an individual patient raises the question of potential harm to others. A prevailing paradox in antibiotic therapy is that what is good for the one may be bad for the many.
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CDC Atlas Tool Maps out Resistant Bug Threat
Trying to get a literal picture of the prevalence and geographic distribution of antibiotic-resistant bacteria in the U.S., the CDC has created an electronic, interactive map that can be accessed on the Web or through a mobile app. The Antibiotic Resistance Patient Safety Atlas reports the percentage of various healthcare-associated infections caused by antibiotic-resistant bacteria.
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Prevent the Bug, Save the Drug:
Once largely consigned to separate silos, infection prevention and antibiotic stewardship are starting to show signs of a powerful partnership. The CDC’s most recent update on the threat of antibiotic-resistant bacteria emphasizes that drug stewardship and infection control must essentially be inseparable if they are going to be successful.