Infectious Disease
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Menopausal Hormone Therapy: Useful and Indicated for Vasomotor Symptoms
Menopausal hormone therapy is the most effective treatment for symptoms of the menopause, and benefits may exceed risks for most women within 10 years of menopause.
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Drug-resistant Hypertension? Consider Adding a Nonpharmacologic Prescription
In patients with obstructive sleep apnea and hypertension, continuous positive airway pressure use was associated with clinically and statistically significant reductions in blood pressure for both resistant and non-resistant hypertension.
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Chest Pain and Giant T Wave Inversion
Chest pain (rather than shortness of breath) and ST elevation (rather than T wave inversion) in leads V1 and V2 make massive pulmonary embolism unlikely.
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Clinical Briefs
In this section: the insulin misadministration problem; comparing smoking cessation pharmacotherapies; more support for ambulatory BP monitoring.
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Tenofovir Alafenamide vs Tenofovir Disoproxil Fumarate
Tenofovir alafenamide has replaced the tenofovir disoproxil fumarate component of two commonly used drug combinations for HIV-1 infection.
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ICH May Clinically Mimic TIA
In a large retrospective review of 2137 patients with intracerebral hemorrhage, 34 presented with transient symptoms that could have been misclassified as “transient ischemic attack” if brain imaging had not been performed.
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Selecting Patients for Statin Primary Prevention
The new vascular disease risk calculator discriminates who will experience a vascular event in the near future better than using a trial entry criteria approach or a hybrid approach.
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Is Anticoagulant Bridging Needed in Patients with Atrial Fibrillation Going to Surgery?
In patients with atrial fibrillation who had warfarin treatment interrupted for an elective operation or other elective invasive procedure, forgoing bridging anticoagulation was not inferior to perioperative bridging with low molecular weight heparin for the prevention of arterial thromboembolism and decreased the risk of major bleeding.
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Infectious Disease Alert Updates
TB in Captive Elephants in the United States; TB Skin Testing and IGRA: An Ongoing Source of Confusion; LASIK, Humidifiers, and Mycobacterium chelonae Ocular Infections
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Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.