Infectious Disease
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Steroids Increase the Risk for Community-acquired Staphylococcus aureus Bacteremia
A case-control study observed an increased risk for developing community-acquired Staphylococcus aureus bacteremia with the use of systemic glucocorticoids. A distinct dose-response relationship was found.
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Antibiotics, Breastfeeding, and the Intestinal Microbiota
Breastfeeding is associated with less frequent bacterial infections and with less subsequent obesity. Using antibiotics reduces or removes these favorable effects of breastfeeding, perhaps via alterations in the intestinal microbiota.
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Guideline Update: Adults with Hospital-acquired and Ventilator-associated Pneumonia
The most notable new recommendation of the updated hospital-acquired pneumonia/ventilator-associated pneumonia guideline may be its endorsement of limiting the duration of antibiotic therapy to seven days in most cases.
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Varicella Zoster Virus and Granulomatous Arteritis
Varicella zoster virus antigen was identified in 11 of 11 aortas with pathologically verified granulomatous arteritis and in only five of 18 control aortas from surgical or autopsy specimens.
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Clinical Briefs
In this section: debunking an asthma treatment; more questions than answers with perioperative statin treatment; and another reason to stay away from cocaine.
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Lixisenatide Injection (Adlyxin)
Lixisenatide is indicated as an adjunct to diet and exercise to improve glycemic control in adults suffering from type 2 diabetes mellitus.
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Dual Antiplatelet Therapy Appears More Effective Than Single Therapy
It appears short-term dual antiplatelet therapy is superior to prolonged treatment, but a difference in outcome must be confirmed by further well-designed randomized, clinical trials.
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Greater Weight Loss Later in Life Associated with Increased Risk of Mild Cognitive Impairment
In a population-based, prospective study of subjects ≥ 70 years of age, increasing weight loss per decade from midlife to late-life was associated with an increased risk of incident mild cognitive impairment.
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Wheat Causes Intestinal Immune Activation in Some Patients Without Celiac Disease
Some patients without celiac disease may exhibit wheat sensitivity with demonstrated intestinal epithelial cell damage.
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Too Little of a Good Thing Can Be a Bad Thing
A healthy lifestyle may substantially reduce the burden of cancer.