Infectious Disease
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Etelcalcetide Injection (Parsabiv)
Etelcalcetide is indicated for secondary hyperparathyroidism in adult patients presenting with chronic kidney disease and who are on hemodialysis.
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Discharge Antibiotic Prescriptions Often Are Inappropriate With Regard to Choice, Dose, Duration
Seventy percent of discharge antibiotic prescriptions are inappropriate.
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American Heart Association Recognizes Cardiorespiratory Fitness Should Be Incorporated Into Risk Calculators
Recognizing the many years of data linking cardiorespiratory fitness to cardiovascular and overall mortality, the American Heart Association says cardiorespiratory fitness should be measured or estimated routinely in patients and added to cardiovascular risk calculators.
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Role of Statins in Venous Thromboembolism Prevention
A large-scale systematic review and meta-analysis found a 15-25% reduction in relative risk for venous thromboembolism in those who used statins vs. those who did not.
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Infectious Disease Alert Updates
Ebola Preparedness in Hospitals; Meningococcal Vaccine Recommended for HIV+ Persons
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Adult Immunizations — 2017 Changes
Significant changes in recommendations for adult immunization for 2017 have been made or influenza, meningococcal infection, human papillomavirus, and hepatitis B.
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Listeria Monocytogenes: Maternal-fetal Infection, Bacteremia, and Meningoencephalitis
Infection with Listeria monocytogenes in pregnancy is associated with frequent fetal loss. In others, bacteremia and central nervous system infections are associated with significant mortality.
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Antibiotic Treatment in Community-acquired Pneumonia
In patients with newly diagnosed community-acquired pneumonia, basing the duration of antibiotic treatment on clinical stability criteria led to a significant reduction in duration of antibiotic treatment without an increased risk of adverse outcomes.
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Does Tonsillectomy Decrease Throat Infections?
For children with recurrent throat infections, tonsillectomy leads to fewer throat infections and less school absence during the first post-operative year (as compared to similar children who did not undergo tonsillectomy). However, beneficial effects of surgery do not persist over time.
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Inflammation in HIV Also Is Mediated by CD8+ T-cells and Platelets
CX3CR1+ CD8+ T-cells home to vascular endothelium and are enriched in ART-treated patients with HIV. These cells may play an important role in CVD risk in HIV-infected patients.