Infectious Disease
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Antibiotic Use in Children — a Cross-national Analysis
Up to 7.5-fold differences in antibiotic use in children were seen across six developed countries in Europe, Asia, and North America. The highest rate of antibiotic use was in Korea, and the lowest was in Norway.
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Clindamycin Improves Outcomes in Necrotizing Fasciitis Due to Group A Streptococcus
Using a murine model of necrotizing fasciitis, investigators determined that clindamycin inhibits key virulence factors of Group A Streptococcus, and should be given as soon as possible and at high doses to reach levels above MIC in affected tissues.
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Vitamin D to Prevent Acute Respiratory Infections?
Vitamin D supplementation is associated with a decreased risk of respiratory infections, especially in those who had low circulating levels of 25-hydroxyvitamin D.
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Clinical Briefs
In this section: soothing dementia with music; the gastrointestinal tract and cardiology; NSAIDs might pose cardiovascular risks.
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Deflazacort Tablets and Suspension (Emflaza)
Deflazacort is indicated for the treatment of Duchenne muscular dystrophy in patients ≥ 5 years of age.
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Antibiotic Treatment in Community-acquired Pneumonia
In patients with newly diagnosed community-acquired pneumonia, basing the duration of antibiotic treatment on clinical stability criteria led to a significant reduction in duration of antibiotic treatment without an increased risk of adverse outcomes.
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Helping Disabled Patients Through Physical Activity
Recent trial demonstrated that a structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not all disability in older adults who experience functional limitations.
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Benefit of Bariatric Surgery for Obesity and Diabetes Maintained After Five Years
It seems that for an individual patient, clinicians now can discuss the pros and cons of bariatric surgery compared with aggressive medical management with a fair bit of certainty about expected outcomes.
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Are There Definitive Clues?
How certain are you that the run of wide complex tachycardia that begins with beat #4 is ventricular tachycardia?
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Clinical Briefs
In this section: targeting the culprit of obesity; a skeptical look at urinalysis; and comparing treatments for peripheral artery disease.