Infectious Disease
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Very Low-carbohydrate Ketogenic Diet May Reverse Type 2 Diabetes
A very low-carbohydrate ketogenic diet demonstrated superiority to the plate method diet recommended by the American Diabetes Association for controlling and even reversing type 2 diabetes.
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No Single Solution to Prevent Medication Nonadherence
Simple, low-cost reminder pill bottles did not lead to more improvement in medication adherence in patients with documented poor adherence.
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Should the Treatment Response Cause Alarm?
The rhythm in the figure was observed as a previously healthy young adult was receiving treatment for the patient described as 'palpitations.'
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Clinical Briefs
In this section: drug therapy for diabetes; timing surgical knee and hip replacement; and treating low back pain.
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Brigatinib Tablets (Alunbrig)
Brigatinib is indicated for the treatment of patients with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.
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Fludrocortisone for Orthostatic Hypotension Associated with Parkinson’s Disease
This double-center, double-blind, randomized, controlled trial compared the efficacy of pyridostigmine bromide vs. fludrocortisone and demonstrated that pyridostigmine bromide was not as effective as fludrocortisone.
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Risk Factors for Hospital Readmissions Ending in Death or Transition to Hospice
In this retrospective cohort study, multiple factors were identified during initial hospitalization, including sepsis and shock, that were associated with a hospital readmission within 30 days resulting in death or transition to hospice.
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Safe Treatment Recommendations for Benzodiazepine Dependence
There are clear, evidence-based treatment withdrawal regimens for benzodiazepine-dependent patients.
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Infectious Disease Alert Updates
Colistin Resistance in Action; PK-tailored High-dose Colistin May Not Be Beneficial; ‘Dragon’s Blood’ Yields Possible Antibacterial
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Oral Cholera Vaccine and Travelers
The new oral cholera vaccine is recommended for adults 18-64 years of age who are planning to travel to areas at risk.