Infectious Disease
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Long-term Use of Proton Pump Inhibitors and Earlier Death
An observational study of a Veterans Affairs population showed that the use of proton pump inhibitors over a median 5.7-year follow-up period increased the risk of death by 25% compared with the use of histamine 2 blockers or no medication.
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Infectious Disease Alert Updates
How Dirty Is That Sandbox?; Rebuilding the Pyramids; Resistant TB in India: Unrecognized Mutations
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GASP! Increasing Worldwide Antibiotic Resistance in Neisseria gonorrhoeae
Antibiotic-resistant gonorrhea threatens to make the infection untreatable in some patients.
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Azithromycin for Chronic Persistent Asthma
Azithromycin reduced exacerbations and improved quality of life in patients with chronic persistent asthma.
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Tetracycline for Multiple Sclerosis?
One hundred forty-two patients within 180 days of their first demyelinating event were randomized to minocycline 100 mg BID vs. placebo. The unadjusted risk of conversion to multiple sclerosis within six months after randomization was 61.0% in the placebo group and 33.4% in the minocycline group. At 24 months, the effect of minocycline was not statistically significant.
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Cefazolin Leads to Better Outcomes for Methicillin-susceptible Staphylococcus aureus Bacteremia Than Nafcillin or Oxacillin
A retrospective study that included patients from 119 Veterans Affairs hospitals found lower mortality and a similar recurrence rate for methicillin-susceptible Staphylococcus aureus bacteremia treated with cefazolin compared to nafcillin and oxacillin.
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Neonatal Group B Streptococcal Bacteremia Associated With Placentophagy
Associated with a mother’s ingestion of encapsulated placenta, an otherwise healthy newborn developed and, with antimicrobial treatment, recovered from both early and late onset group B streptococcal bacteremia. This is apparently the first report of a serious negative consequence of maternal consumption of dried placenta.
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Ebola Outbreak Ends; Lessons of 2014 Resonate
The WHO declared the end of the most recent outbreak of Ebola virus on July 2, 2017, saying two 21-day incubation cycles had passed since the last confirmed case in the Democratic Republic of the Congo. There were eight cases, four of whom died.
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Why Antibiotic Stewardship Teams Need IPs
Patti Kieffer, BSN, RN, CIC, FAPIC, infection prevention consultant at BJC HealthCare in St. Louis, had a much different talk in mind when she originally thought of addressing her IP colleagues on the antibiotic stewardship.