Infectious Disease
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What Can Be Said With LBBB?
The ECG in the figure was obtained from a patient with new-onset chest pain. It was interpreted as showing complete left bundle branch block (LBBB). Thus, the provider reasoned that “it is impossible to tell if anything acute is going on because there is LBBB.” Do you agree with that assessment?
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Clinical Briefs
In this section: Managing postprandial glucose excursions in diabetic patients, strategies for improving long-term outcomes for obesity patients, and effectively treating Crohn's disease.
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Vancomycin HCl for Oral Solution (Firvanq)
Vancomycin oral solution is indicated for adults and pediatric patients < 18 years of age for Clostridium difficile-associated diarrhea and enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains).
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Aerobic Exercise and Cognitive Impairment
Progressive aerobic exercise training appears to be a low-risk and effective intervention for improving cognitive function in community-dwelling adults with mild subcortical ischemic vascular cognitive impairment.
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Type 2 Diabetes Is Reversible
Type 2 diabetes is reversible (or can be put in remission) in a primary care practice through an intense low-carbohydrate weight management program.
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Infectious Disease Alert Updates
Food Tray Contamination With MRSA/VRE; Hospital Ice Machines Contaminated With Bacteria; Significance of Toxocara Serologies?
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What Do the Urinary Microbiota and Incontinence Have to Do With Each Other?
Increased diversity of the microbiota in women is associated with urgency urinary incontinence symptoms but not with stress urinary incontinence symptoms.
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Does Adding Rifampin to Standard Therapy Improve Outcomes in Patients With Staphylococcus aureus Bacteremia?
The addition of rifampin to standard therapy failed to provide significant benefit to patients with bacteremia due to Staphylococcus aureus.
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New Agent for Treatment of Chagas Disease Disappoints in Clinical Trial
A randomized, controlled trial of E1224 (a ravuconazole prodrug) in different doses and durations was studied in adult patients with chronic indeterminate Chagas disease. Parasite clearance was observed in treated patients, but the response was transient in most patients.
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Mefloquine: Still Effective and Still Safe for Malaria Chemoprophylaxis
Mefloquine is known as an effective agent for malaria chemoprophylaxis. However, concerns about serious adverse effects have limited its use. Now, a careful review of data suggests that fatal outcomes related to mefloquine prophylaxis are very rare.