Infectious Disease
RSSArticles
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Adjuvanted Recombinant Hepatitis B Vaccine (Heplisav-B)
Heplisav-B is a new hepatitis B vaccine approved by the FDA in November 2017.
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Influenza Vaccine: High Dose or Standard Dose?
High-dose inactivated influenza vaccine was superior to standard-dose vaccine in providing protection against influenza or pneumonia-associated hospitalizations.
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Refugee Screening
Screening and potential treatment of refugees prior to travel to the United States effectively reduces the burden of infection.
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SIRS Criteria vs. qSOFA for Predicting Short-term Mortality From Sepsis
A meta-analysis that included 38 studies found the SIRS criteria had a higher sensitivity than qSOFA in predicting short-term mortality from sepsis. SIRS criteria remain useful as a screening tool for sepsis and as a prompt to initiate diagnostic work-up and treatment.
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Neuroimaging Before Lumbar Puncture?
The investigators retrospectively evaluated ESCMIID, IDSA, and Swedish guidelines for neuroimaging in 815 adults with acute bacterial meningitis. Swedish guidelines omit altered mental status and immunosuppression as indications for imaging prior to lumbar puncture. Adherence to Swedish guidelines resulted in decreased mortality and more favorable outcomes.
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Clinical Briefs
In this section: improving cardiovascular outcomes in type 2 diabetes patients; digging deeper into penicillin allergies; and treating osteoporosis.
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Apalutamide Tablets (Erleada)
Apalutamide is indicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer.
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Providers Facilitate Transmission of Resistant Organisms
A closer look at the role providers play in the transmission of carbapenem-resistant Enterobacteriaceae.
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Physician Burnout: A Multi-specialty Perspective
Although different specialties address the problem of physician burnout, studies suggest the most effect is gained from organizational interventions.
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Another Reason to Get the Flu Shot Every Year
In a case-control study, among older adults, repeated vaccination for influenza was twice as effective in preventing severe influenza compared to non-severe influenza in patients who were admitted to the hospital.