Infectious Disease
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Tolvaptan Tablets (JYNARQUE)
Tolvaptan is indicated to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease.
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Rapid Screening for Future Risk of Parkinson’s Disease Dementia
The Montreal Parkinson Risk of Dementia Scale provides a simple eight-item screening tool with high predictive value for developing Parkinson’s disease dementia.
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Combined Treatments with Medications for Hypertension and Hyperlipidemia Dramatically Reduce the Risk of Stroke
In this real-world study, fixed-dose candesartan/hydrochlorothiazide combined with low-dose rosuvastatin reduced first stroke by 44% in patients at intermediate risk of cardiovascular disease and was well tolerated, with minimum dropout of patients.
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Chiropractic Spinal Manipulation for Migraine
Chiropractic spinal manipulation offers no benefit over placebo for migraineurs.
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The Pulmonary Embolism Rule-out Criteria in Low-risk Patients
A cluster randomized trial of the pulmonary embolism rule-out criteria (PERC) compared to usual care for patients estimated to be at low risk of pulmonary embolus (PE) in EDs showed that PERC was non-inferior to usual care at identifying patients who would be free of symptomatic PE at three months, resulting in less use of healthcare resources.
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Hair Apparent: Surgeon Rebellion Succeeds on Head Covers
Previous recommendations for surgeons to fully cover their hair and ears to prevent infections have probably been observed more in the breach than the observance.
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Flu Mandates: Consider Accommodations and Avoid a Lawsuit
Legal challenges to vaccination mandates can be avoided if hospitals try to provide some alternative accommodation for those claiming religious exemption. -
Fauci: HIV Can Be Stopped, but Vaccine Remains Elusive
One of the great pandemics in human history has been fought to a near draw, with no vaccine in sight but treatments that dramatically extend life and block transmission to others. -
Consider Probiotics in Patients at High Risk of C. diff Infection
After the most exhaustive analysis to date on the efficacy of probiotics in preventing Clostridium difficile infection, a researcher recommends that high-risk patients consider taking the products.
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HICPAC Taking New Approach to IC Recommendations
The Centers for Disease Control and Prevention’s principle infection control advisory committee is taking steps to clarify its recommendations, be more transparent about its review of research, and, to paraphrase Voltaire, quit making “perfect the enemy of good.”