Infectious Disease
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AFM Peaking Every Other Year
In an unusual pattern that adds to the mystery of acute flaccid myelitis (AFM), the paralytic syndrome in children is peaking every other year in a fall seasonal pattern that began in 2014. -
Tips and Info on AFM From an Experienced IP
Sue Dolan, RN, an infection preventionist at Colorado Children’s Hospital in Denver, has extensive experience dealing with acute flaccid myelitis (AFM) and the viruses that can trigger the paralytic condition. She provided tips for IPs to Hospital Infection Control & Prevention.
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What Is Causing Acute Flaccid Paralysis Syndrome in Children?
The recent increase of acute flaccid myelitis (AFM) in pediatric patients has parents distraught and investigators looking at more questions than answers. Typical onset includes weakness in the arms and legs, with the median age of afflicted children being four years old.
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Infectious Disease Alert Updates
Metagenomics for Prosthetic Joint Infection; Helicobacter pylori: A Mini Primer
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Severe Sepsis and Septic Shock Early Management Bundle
When the Severe Sepsis and Septic Shock Early Management Bundle was used to identify patients with severe sepsis or patients in septic shock, delays in lactate measurements for patients with abnormal lactate levels were associated with delayed initiation of antibiotic therapy and increased mortality.
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Healthcare-associated Infections — Better, But Not There Yet
One-day prevalence studies demonstrated that there has been a 16% reduction in the risk of healthcare-associated infections from 2011 to 2015.
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Oral Linezolid for Staphylococcus aureus Bacteremia
Investigators evaluated 135 patients with Staphylococcus aureus bacteremia (SAB) in a prospective cohort study comparing early switch to oral linezolid to continued treatment with standard parenteral therapy (SPT). Patients with complicated SAB and osteoarticular infection were excluded. Early switch to oral therapy yielded similar outcomes to continued SPT and allowed earlier hospital discharge.
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Factors Associated With Urinary Tract Infections Caused by Multidrug-resistant Gram-negative Bacteria
A multicenter, retrospective, cohort study from southern and eastern Europe identified predictive factors for multidrug-resistant complicated urinary tract infections (cUTI), which included male sex, cUTI acquisition in a healthcare facility, presence of a Foley catheter, having a UTI in the previous year, and receiving an antibiotic in the preceding 30 days.
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Blastomycosis (But Not That Blastomycosis) in the Western United States
Blastomycosis occurs in western Canada and in the United States well outside the known endemic area, but it is due to Blastomyces helicus, not Blastomyces dermatitidis.
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Optimal Treatment of Vivax Malaria
In glucose-6-phosphate-dehydrogenase-sufficient individuals in Southeast Asia, combined treatment with chloroquine and primaquine provides much more lasting relief from vivax malaria than either chloroquine alone or artesunate.