Infectious Disease
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Duration of Intravenous Antibiotic Therapy for Late-Onset Neonatal Group B Streptococcal Bacteremia
Although standard treatment of late-onset neonatal group B Streptococcus bacteremia includes intravenous antibiotic therapy for 10 days, shorter courses seem safe and effective.
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A Nosocomial Outbreak at the NIH Clinical Center From Sphingomonas koreensis, a Rare Human Pathogen
A genomic and epidemiologic investigation of an outbreak at the National Institutes of Health Clinical Center determined that S. koreensis was an opportunistic human pathogen that persisted in a reservoir in the hospital plumbing.
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Treatment of Gram-Negative Bacteremia: How Long Is Long Enough?
Antibiotic administration for seven days is sufficient in stable patients with Gram-negative bacteremia.
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A ‘Detective’ Diagnosis
The ECG in the figure was obtained from a 40-year-old man. Without the benefit of any history, how might one interpret this tracing? Is there evidence of an acute coronary syndrome? Is there a common diagnosis that potentially explains all the findings?
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Rifamycin Delayed-Release Tablets (Aemcolo)
Rifamycin is indicated for the treatment of traveler's diarrhea caused by noninvasive strains of Escherichia coli in adults.
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Patients Need to Rethink the ‘Quality’ in Healthcare
Increasingly, patient satisfaction is an important and commonly used surrogate marker for healthcare quality. Further, reimbursement to physicians may be based on patient satisfaction as a “quality” metric. But the evidence linking a patient’s subjective sense of satisfaction and the actual delivery of quality care remains tenuous.
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Healthcare-Associated Infections: Better, But Not There Yet
One-day prevalence studies demonstrated that there was a 16% reduction in the risk of healthcare-associated infections from 2011 to 2015.
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Factors Associated With Urinary Tract Infections Caused by Multidrug-Resistant Gram-Negative Bacteria
The authors of a multicenter, retrospective, cohort study from southern and eastern Europe identified predictive factors for multidrug-resistant complicated urinary tract infections.
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A Review of Updated Guidelines Regarding Bradycardia and Cardiac Conduction Delay
The American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society have established updated guidelines on the evaluation and management of patients with bradycardia and conduction delays. Many key elements remain largely unchanged from prior guideline recommendations on pacemakers published in 2008 and 2012, but there are important new definitions, recommendations, and areas of emphasis.
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New Drugs Needed for Bad Bugs
To stem the tide of antibiotic-resistant pathogens, the FDA will provide more incentives and market opportunities in 2019 as part of a five-year plan to get the pharmaceutical industry involved in restoring the dwindling drug pipeline.