Infectious Disease
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Spotted Fever Rickettsioses and Meningoencephalitis
Researchers reviewed 19 cases of meningoencephalitis associated with spotted fever rickettsioses. Fever was present in all cases. Rash was present in 100% of pediatric patients but in only 50% of adult patients. Cerebrospinal fluide pleocytosis was present in 88% of patients. Ninety percent of patients required ICU admission, and only 46% of patients recovered completely.
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Febrile Urinary Tract Infection in Young Infants — Value of Spinal Fluid Analysis
Practices vary significantly as clinicians evaluate and manage febrile infants younger than 2 months of age. A retrospective review suggests that meningitis is extremely unlikely in well-appearing babies with initial laboratory results suggestive of urinary tract infection, and that cerebrospinal fluid analysis may not be necessary.
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Urinary Tract Infection With Bacteremia in Young Infants: Duration of Parenteral Therapy
The duration of parenteral antimicrobial therapy for bacteremic urinary tract infection in young infants varies between practitioners and centers. A retrospective review suggests that extending parenteral treatment beyond seven days does not alter outcomes.
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Vaping and Severe Acute Pneumonitis
As of Aug. 27, 2019, 215 cases of severe pulmonary disease possibly related to vaping have been reported to the CDC. Evidence to date suggests the illness is a form of acute lipoid pneumonia likely related to inhalation of lipid materials. -
Trained Dogs Detect C. diff in the Environment
A Canadian hospital is using highly trained dogs to sniff out C. diff in the environment, in a methodical manner akin to the way canines find drugs and explosives.
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CDC Drafts Infection Control Guidelines for Staph in NICUs
The Centers for Disease Control (CDC) has issued draft guidelines to prevent invasive Staphylococcus aureus infections in neonatal intensive care units (NICUs). -
ID Groups Demand Border Patrol Give Detainees Flu Shots
The U.S. Customs and Border Protection’s (CBP) decision to not vaccinate migrants in detention facilities against flu and other infections is being slammed by leading clinicians and public health officials. -
Sepsis Can Begin With a Single Infection
The goal of antibiotic stewardship is to stop unnecessary use, but for those with sepsis, a critical step is to assess antibiotic therapy 48 to 72 hours after initiation.
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IPs Playing Critical Role in Antibiotic Stewardship
Infection preventionists (IPs) are playing key roles in antibiotic stewardship programs, which are now in place in most U.S. hospitals and making some hard-earned progress against a horde of multidrug-resistant bacteria. -
Darolutamide Tablets (Nubeqa)
Darolutamide should be prescribed to patients with nonmetastatic, castration-resistant prostate cancer.