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Infectious Disease

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  • Pharmacology Watch: CDC Adds Shingles Vaccine to List for Adults 60 Plus

    In This Issue: Shingles vaccine added to CDC list of vaccines for adults 60 and older; CDC recommends Tdap for postpartum women; new study suggests sequential therapy with antibiotics for H. pylori may be more effective than standard therapy; FDA Actions.
  • Serum (1 --3) B-D-glucan Assay for Diagnosis of Invasive Fungal Infection

    For this study, 279 patients from five groups (including 70 with proven or probable invasive pulmonary aspergillosis, 27 patients with blood cultures positive for a fungal pathogen, and 20 with PCP) were BG levels were measured with the Fungitell test kit.
  • Whither PANDAS?

    A blinded, prospective, case-control study of 40 children meeting all of the DSM-IV criteria for PANDAS matched with 40 children with obsessive-compulsive disorder and/or a chronic tic disorder was conducted with periodic intensive laboratory testing for group A streptococcus for 2 years, especially with clinical exacerbations or acute illness.
  • Pseudo Fever Due to Mucositis

    In this study, 100 consecutive patients, who were receiving several different cytotoxic chemotherapy regimens for a variety of cancers, were self-referred on the basis of perception of mucositis, elevated temperature at home, malaise, or were referred by a nurse based on assessment of potential infection or mucositis.
  • Excluding Bacteremia in Children with Central Venous Catheters

    A retrospective, cohort study of 200 episodes randomly selected from 315 episodes, during 2000-2003, at Children's Hospital of Philadelphia, of laboratory-confirmed bloodstream infections among out-patient children with central venous catheters was performed to determine the optimum duration of antibiotic therapy before infection could be reliably excluded.
  • Pneumococcal Vaccine has Changed the Epidemiology of Pneumococcal Meningitis

    The impact of 7-valent pneumococcal conjugate vaccine (PCV7) was studied using the Nationwide Inpatient Sample, which is the largest source of inpatient data in the United States and drawn from about 1000 community hospitals.
  • For the Record...

    This group of health policy leaders sought to learn the proportion of physicians who are currently using electronic health records, whether they were satisfied with the systems they used, and what impact the physicians believe that these systems have on quality of patient care.
  • How Should We Interpret Pulmonary Crackles?

    Pulmonary crackles (the physical finding previously known as râles, French for "rattle") are commonly sought to confirm a diagnosis of heart failure (HF) and can be fine, medium, or coarse. However, crackles can occur in other diseases (interstitial lung disease, asbestosis, alveolitis, and bronchiectasis) and in presumably normal people.
  • Full July 29, 2008 Issue in PDF

  • Clinical Briefs by Louis Kuritzky, MD

    Allergic rhinitis is often treated successfully with antihistamines and local corticosteroids, but because of inadequate symptom control, patient preference, or both, sometimes allergen desensitization becomes preferable.