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A randomized controlled trial showed that low-dose colchicine, 1.2 mg initially followed by 0.6 mg at 1 hour, was equally effective with fewer side effects as high-dose colchicine, eight 0.6 mg pills over 6 hours. The < 40% response rate with 23% getting diarrhea in the low-dose group calls into question whether colchicine is the superior choice over NSAIDs for acute gout.
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New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions.
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The ECG shown above was obtained from an 88-year-old woman who refused treatment. What is the rhythm? Is there a grouping? Is anything else going on?
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Because it is recognized that type 2 diabetics (DM2) incur greater risk of CV outcomes than the general population, consensus groups have advocated BP < 130/80 mmHg as a preferred goal, in contrast to 140/90 mmHg for the general hypertensive population.
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In community-dwelling women age 70 years and older, annual oral administration of high-dose vitamin D for 3-5 years resulted in a higher, not lower, incidence of falls and fractures.
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Vitamin B12 levels fall, and continue to fall, with continued metformin use in patients already receiving insulin.
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Ketorolac nasal spray is indicated for the management of moderate to moderately severe pain that requires analgesia at the opioid level.1 It is indicated for short-term use only (up to 5 days).
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Despite dramatic and widely reported breakthroughs in preventing bloodstream infections, the cold truth is that too many infection preventionists labor in obscurity, their programs woefully underfunded by administrators blind to the power of prevention.
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Infection preventionists must seize an extraordinary moment in health care, when divergent forces are aligning to redesign a system that has failed to contain costs and protect the lives to which it has been entrusted, Atul Gawande, MD, MPH, said recently in New Orleans in the keynote address at the 37th annual educational conference of the Association for Professionals in Infection Control and Epidemiology (APIC).