Infectious Disease
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Acute Myocardial Infarction, or Acute Pericarditis?
The lack of significant Q waves, lack of any reciprocal ST depression, and the prominent J-point notching in the figure all suggest this may not be an acute infarction.
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Ozanimod Capsules (Zeposia)
Ozanimod should be prescribed to treat relapsing multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
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Cannabis for Mental Health Disorders: Follow the Evidence
In a review of 83 eligible studies, researchers found little evidence to support the efficacy of cannabinoids to treat depressive disorders, anxiety disorders, or several other mental health disorders.
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The Cascade Effect: Calcium Channel Blockers and High Blood Pressure
Many older adults who are prescribed calcium channel blockers subsequently receive a loop diuretic. Awareness of this common cascade may reduce unnecessary prescribing and potential harm.
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More Mediterranean Diet Benefits: Diverse Microbiomes, Better Health Among Seniors
A randomized, multicenter study showed that eating a Mediterranean diet for one year improved the diversity of the gut microbiome in older subjects and was associated with reduced frailty and better health.
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Federal Agencies, Pharma Industry Work to Speed COVID-19 Therapeutics, Vaccine
Public-private partnership aims to streamline, coordinate large-scale efforts.
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Infectious Disease Alert Updates
Masking Our Anxiety; Is it Luck or Genetics? Neurologic Infection from SARS-CoV-2
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Evaluation of 2020 Vancomycin Guidelines: Highlights, Limitations, and Obstacles
The key change from the 2009 vancomycin guidelines is the switch from trough-based to area under the curve (AUC)-based dosing and monitoring. This article will highlight key differences between the 2009 and 2020 guidelines, limitations of the new guidelines, and implementation issues.
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Differentiating Clostridioides difficile Infection from Chronic Carriage in Patients with Diarrhea Through Host Inflammatory Markers
Investigators compared levels of inflammatory markers in patients with Clostridioides difficile infection (CDI) to those who were colonized with it. Several markers appeared to be able to distinguish true CDI, although a gold standard definition of CDI is needed.
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.