Infectious Disease
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Remdesivir Injection
Under a federal emergency authorization, remdesivir can be used to treat suspected or laboratory-confirmed COVID-19 in children or adults who are hospitalized with severe disease.
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Brief, Targeted Intervention to Stop Smoking
A one-minute intervention giving facts about the health impact of smoking was presented to men waiting to be seen in Hong Kong emergency rooms. At a six-month follow-up, investigators found a significantly higher abstinence rate in the intervention group.
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Coronary CT Angiography to Identify Plaque Stabilization
Researchers identified subjects with no known coronary artery disease drawn from a large international, multicenter registry of coronary CT angiography. The authors demonstrated those with a high density of calcium plaques experienced the fewest events, suggesting high-density calcium plaques are stable.
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Masking Our Anxiety
Weighing the pros and cons of wearing a face covering in public.
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Public Health Interventions to Reduce COVID-19 Spread
After studying the association of public health interventions with the epidemiological features of the COVID-19 outbreak in Wuhan, China, the authors found nonpharmaceutical interventions may be associated with better outbreak control.
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ACS Prepares Surgeons for Resuming Elective Procedures
The COVID-19 pandemic forced many facilities to press pause on regular operations. Now, some are ready to chart a course back toward some sense of normalcy.
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Infectious Disease Alert Updates
Complications of Typhoid Fever; Do I Smell a Rat? Or Is the Rat Smelling Me? Cloth Masks — Just for Looks?
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Lefamulin: Formulary Considerations
The Food and Drug Administration (FDA) recently approved lefamulin for the treatment of adults with community-acquired bacterial pneumonia (CABP).
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Antibiotic Therapy to Reduce the Incidence of Ventilator-Associated Pneumonia After Cardiac Arrest
In this prospective, randomized trial, intravenous amoxicillin-clavulanate (dosed three times daily and given for two days) administered to patients admitted with out-of-hospital cardiac arrest due to a shockable rhythm reduced the incidence of early ventilator-associated pneumonia.
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Carbapenem-Resistant Enterobacterales (CRE) in the USA — A Molecular and Clinical Analysis
Patient mortality rates were high among patients from whom carbapenem-resistant Enterobacterales (CRE) were cultured, regardless of whether the organism was causing infection or was a only a colonizer. In addition, mortality was similar regardless of whether a carbapenemase gene was present. Finally, not all “CRE” were truly CRE.