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Prison systems are a prime intervention point to stop the silent epidemic of hepatitis C virus (HCV), as millions of people infected with HCV in the United States are in jail or have a history of incarceration.
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FDA Issues Black Box Warning Based on WHI Study; ALLHAT: Thiazide for Hypertension Treatment; Candesartan Effective Against Migraines; Cough! No Cold Relief from Echinacea; COX-2 Inhibitors and GI Benefits Could Be Overrated; FDA Actions;
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This article reviews multiple aspects of heart failure, providing direction for workup and management of heart failure patients. All recommendations follow current published guidelines. Unresolved and controversial issues are reviewed, and future therapies are proposed.
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Treatment with natalizumab, an antibody to a4 integrin, led to fewer inflammatory brain lesions and fewer relapses in patients with relapsing multiple sclerosis.
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Current guidelines for NSAID use in patients at high risk for ulcer disease recommend use of NSAIDs selective for cyclo-oxygenase-2 inhibition or nonselective NSAIDs plus a proton pump inhibitor. This study compared diclofenac plus omeprazole with celecoxib in patients with previous GI hemorrhage. Neither regimen successfully prevented rebleeding, and both exhibited significant toxicities.
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Screening for lung cancer with helical CT has high costs and uncertain benefits.
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Ice Cream-Evoked Headaches Study: A Randomized Trial of Accelerated vs Cautious Ice Cream Eating Regimen; Treatment of Antidepressant-Associated Sexual Dysfunction with Sildenafil; Prophylactic Treatment of Migraine with an Angiotensin II Receptor Blocker