Infectious Disease Topics
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Infectious Disease Alert Updates
Diagnostic Puzzle? Solved by The New York Times; Glucometers as Culprit; Shorter Isolation Times for TB
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Clinicians Are Skeptical of Early Warning Systems for Sepsis
While early warning systems for sepsis lead to clinical action, clinicians are skeptical and do not perceive them to be beneficial.
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Posaconazole Dosing — Beware!
The availability of two different oral formulations of posacozaole (oral suspension, delayed release tablets) with differing bioavailability and dosing requires great care by both prescribers and dispensing pharmacists in their use.
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Bronchiolitis
Bronchiolitis is a common infection caused by several different viruses; 20% of children in the United States seek medical care for respiratory syncytial virus , a common cause of bronchiolitis, during the first year of life. Supportive care is effective, but many children still receive pharmacologic treatments that have been proven to be ineffective.
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Outbreaks of Salmonellosis Associated with Turtles
Eight outbreaks with 473 cases of salmonellosis associated with small turtles occurred in the United States from 2011-2013, despite the 1975 ban of the sale and distribution of small pet turtles. The outbreaks disproportionately affected children younger than 5 years of age (55% of case-patients) and Hispanics (45% of case-patients).
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Both Azithromycin and Doxycycline Achieve a High Rate of Cure for Chlamydia
Although a well-conducted randomized clinical trial did not show that azithromycin was non-inferior to doxycycline for the treatment of chlamydia, both treatments resulted in a high rate of cure (97% and 100%, respectively).
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Next-generation Sequencing to Diagnose Cryptic Hep B and E
ABSTRACT & COMMENTARY: Sera from patients with hepatitis of unknown etiology were studied using next-generation sequencing.
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Infectious Disease Alert Updates
These updates include: "A Deadly Funeral", "Increase in Congenital Syphilis", "That Is Not Strep Throat!", and "Increase in Ocular Syphilis"
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Malaria: Getting Better, but Still a Long Way To Go
While significant progress has been made in the control of malaria, the number of cases remains huge — an estimated 198 million cases and 584,000 deaths in 2013.
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Antibiotic Therapy for Pediatric Parapneumonic Empyema
In a retrospective review of 391 children with parapneumonic empyema, the safety and effectiveness of oral antibiotic therapy was comparable to outpatient parenteral antibiotic therapy for antibiotic management following hospitalization.