Infectious Disease Topics
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Infectious Disease Alert Updates
Borrelia Miyamotoi in My Backyard! Who Knew?
Fecal Microbiota Transplantation — Patients Need No Convincing
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Malaria in Pregnancy — Good News, Bad News, and Opportunity
With waning natural immunity against malaria, women face increased adverse consequences of malaria infection during pregnancy. As malaria is being conquered, good clinical care of vulnerable individuals is still essential.
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Ceftazidime-avibactam — Formulary Considerations
Ceftazidime-avibactam is a new beta-lactam/beta-lactamase inhibitor combination approved for the treatment of complicated intra-abdominal infections in combination with metronidazole, and complicated urinary tract infections, including pyelonephritis in patients with limited alternative treatment options.
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ID Grand Rounds — Stanford University
A 69-year-old male with allogeneic hematopoietic stem cell transplant with a space-occupying lesion of the central nervous system.
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Tissue Invasion by Malignantly Transformed Cells from Hymenolepis nana in a Human Host
The first reported case of human disease caused by parasite-derived cancer cells was discovered in a 41-year-old man with HIV infection; lung, adrenal, and liver nodules; and lymphadenopathy.
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Outcomes of Acute Encephalitis in Children
ABSTRACT & COMMENTARY: MRI is useful not only in assisting with identifying the etiology of encephalitis, but also provides prognostic information.
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Infectious Disease Alert Updates
Meningitis Diagnostics
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Anti-parasitic Therapy of Chronic Chagas’ Cardiomyopathy
Two thousand eight hundred fifty-four patients with Chagas’ cardiomyopathy were randomized to benznidazole or placebo, were treated for up to 80 days, and were followed for a mean of 5.4 years. Trypanocidal treatment with benznidazole reduced serum parasite detection but did not reduce clinical cardiac deterioration.
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Oritavancin: Formulary Considerations
Oritavancin is a lipoglycopeptide bactericidal antibiotic for intravenous administration with activity against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus.
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Acetaminophen for Fever in the ICU
Seven hundred ICU patients with fever and known or suspected infection were randomly assigned to receive acetaminophen 1 g IV or placebo every 6 hours until ICU discharge, resolution of fever, cessation of antimicrobial therapy, or death. Early administration of acetaminophen did not affect number of ICU-free days.