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Evaluation of Amoxicillin Allergy in Children

The majority of children in this study were nonallergic. Provocative challenges should be conducted in an appropriate medical setting.

Skin Infections in Student Athletes

Among high school and college athletes, skin infections are most common in wrestlers and football players. Bacterial infections predominate. Up to 22% of wrestlers are colonized with methicillin-resistant Staphylococcus aureus sometime during the season.

Infectious Disease Alert Updates

“A New Wave of World-wide Gastroenteritis?”; Who Wants a Stoma if You Don’t Need One?; A Side of Hep E with Your Pork Roast?

Healthcare Workers and Tuberculosis Prevention

Healthcare workers in high-burden countries in particular remain at high risk of tuberculosis.

Does Finding the Portal of Entry of Bacteria in Infective Endocarditis Matter?

A comprehensive, systematic search for the portal of bacterial entry in infective endocarditis is frequently successful and affords an opportunity to prevent recurrent episodes.

Oral Rehydration for Children with Mild Gastroenteritis

In a randomized study of children 6 to 60 months of age with acute gastroenteritis accompanied by mild vomiting and/or diarrhea with mild or no dehydration, initial oral rehydration with half-strength apple juice/preferred fluids resulted in fewer treatment failures than with electrolyte maintenance solution. In high-income countries, dilute apple juice/preferred fluids may be an acceptable alternative to commercial electrolyte maintenance solutions for childhood mild gastroenteritis with minimal dehydration.

The Seasonality of Childhood Respiratory Infections

Human metapneumovirus infection is increasingly recognized in children. Epidemiologic review suggests that it becomes common each winter after the onset of the respiratory syncytial virus “season” and then continues to cause frequent illness until the spring.

HLH Gene Mutations and Fatal Influenza

Sixteen patients with fatal influenza who underwent autopsy were studied. Thirteen patients (81%) had histopathologic evidence of hemophagocytosis. Five patients (36%) carried one of three heterozygous LYST or PRF1 mutations associated with hemophagocytic lymphohistiocytosis and macrophage activation syndrome.