Infectious Disease Topics
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Infectious Disease Alert Updates
Colistin Resistance in Action; PK-tailored High-dose Colistin May Not Be Beneficial; ‘Dragon’s Blood’ Yields Possible Antibacterial
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Oral Cholera Vaccine and Travelers
The new oral cholera vaccine is recommended for adults 18-64 years of age who are planning to travel to areas at risk.
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Surviving Sepsis Campaign Guidelines Bundle: Studying How Improved Compliance Might Affect Outcomes
Improved compliance with the Surviving Sepsis Campaign guidelines bundle was associated with a non-statistically significant decrease in the in-hospital mortality of severe sepsis patients.
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Ready for Dengue in the United States?
Dengue is increasingly recognized in the southern United States. When recently surveyed, however, clinicians in Texas seemed incompletely prepared to understand and manage patients with dengue.
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Bambi Strikes Again — Encephalitis Due to the ‘Deer Tick Virus’ (Powassan Virus) May Be Increasing in Frequency
Powassan virus is transmitted by the same tick that carries the etiologic agent of Lyme disease and several other pathogens. The number of cases of encephalitis caused by this virus may be increasing in the endemic areas.
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Current Trends and Outcomes for Infective Endocarditis
Using large databases from New York and California, investigators found the overall incidence of infective endocarditis remained stable between 1998 and 2013, and 90-day mortality declined. Changes were noted in pathogen etiology and patient characteristics over time.
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Infectious Disease Alert Updates
Sepsis Survival Affected by Drug Shortage;
A Rare Cause of Eosinophilic Meningoencephalitis;
Look, Ma! I Hooked My Thumb
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Guillain-Barré Syndrome and Hepatitis E
Hepatitis E is the most common form of viral hepatitis worldwide and often is asymptomatic. But it is commonly associated with Guillain-Barré syndrome and Guillain-Barré variants.
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Beta-lactam Antibiotics May Be Useful in MRSA Infection
Using several in vitro assays and animal models, it was shown that oxacillin-treated methicillin-resistant Staphylococcus aureus strains are attenuated in virulence. The effect is mediated by repression of accessory gene regulatory quorum-sensing system and altered cell wall architecture.
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Treatment of Chronic Fatigue/Myalgic Encephalitis Syndrome: Blocking the IL-1 Component to the Inflammatory Response Is Ineffective
Blockade of IL-1 activity with anakinra failed to reduce fatigue in patients with chronic fatigue syndrome.