Infectious Disease Topics
RSSArticles
-
Azithromycin for Chronic Persistent Asthma
Azithromycin reduced exacerbations and improved quality of life in patients with chronic persistent asthma.
-
Tetracycline for Multiple Sclerosis?
One hundred forty-two patients within 180 days of their first demyelinating event were randomized to minocycline 100 mg BID vs. placebo. The unadjusted risk of conversion to multiple sclerosis within six months after randomization was 61.0% in the placebo group and 33.4% in the minocycline group. At 24 months, the effect of minocycline was not statistically significant.
-
Cefazolin Leads to Better Outcomes for Methicillin-susceptible Staphylococcus aureus Bacteremia Than Nafcillin or Oxacillin
A retrospective study that included patients from 119 Veterans Affairs hospitals found lower mortality and a similar recurrence rate for methicillin-susceptible Staphylococcus aureus bacteremia treated with cefazolin compared to nafcillin and oxacillin.
-
Neonatal Group B Streptococcal Bacteremia Associated With Placentophagy
Associated with a mother’s ingestion of encapsulated placenta, an otherwise healthy newborn developed and, with antimicrobial treatment, recovered from both early and late onset group B streptococcal bacteremia. This is apparently the first report of a serious negative consequence of maternal consumption of dried placenta.
-
Infectious Disease Alert Updates
Antibiotic increases honeybee mortality; Sustained hepegivirus infection in injection drug users; Decrease SSIs: Take August off
-
2016 Surviving Sepsis Guidelines Update
The Surviving Sepsis Campaign recently published an update to the 2012 guidelines for management of sepsis and septic shock. The document incorporates literature published through July 2016.
-
Sepsis Management: What We Think We Know
In the Protocolized Resuscitation in Sepsis Meta-Analysis (PRISM), 3,723 patients’ outcomes from the ProCESS, ARISE, and ProMISe randomized, controlled trials of early goal-directed therapy (EGDT) were evaluated. EGDT did not result in better outcomes than usual care and was associated with higher costs. The authors of a second study looked at outcomes of 49,331 patients with sepsis treated in New York from April 2014 to June 2016. More rapid completion of the three-hour sepsis bundle and antibiotic administration (but not rapid bolus administration of IV fluids) was associated with reduced in-hospital mortality.
-
Bug Bytes From Barcelona: Report of the 15th Conference of the International Society of Travel Medicine
In addition to issues of malaria, vaccination, and trauma in travelers, viral diseases and the management of diarrhea were key topics at the biannual meeting of the International Society of Travel Medicine in Barcelona, Spain, during May 2017.
-
Not Just Ebola — Lassa Fever Rears its Ugly Head Once Again
Outbreaks of Lassa fever are occurring in Nigeria and several other West African nations, some of which also are endemic for Ebola virus infections.
-
Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.