Infectious Disease Topics
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A Maternal Antibody Protects Infants From Severe Malaria
Transplacental antibodies against Plasmodium falciparum Schizont Egress Antigen-1 may protect infants from severe malarial infection during the first year of life. This new knowledge about these antibodies potentially can inform vaccine development.
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Mechanism of Persistence of Moraxella catarrhalis in Patients With Chronic Obstructive Pulmonary Disease
This study examines the mechanism that allows Moraxella catarrhalis to persist in some patients with chronic obstructive pulmonary disease.
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Infective Endocarditis Prevalence in Dutch Patients With Positive Blood Cultures
Data from a nationwide registry in Denmark from 2010 to 2017 showed that patients with Enterococcus faecalis bacteremia had the highest prevalence of infective endocarditis (16.7%), followed by Staphylococcus aureus (10.1%) and Streptococcus spp. (7.3%).
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Travel Medicine 2019 — A Conference Report
The International Society of Travel Medicine met in Washington, DC, from June 5-9.
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Measles — It’s Back!
The number of measles cases in the United States has exceeded 1,000 so far in 2019, the largest number in a quarter of a century.
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Infectious Disease Alert Updates
California Inmates With Cocci Lose Appeal; Tuberculosis Testing in Small Children
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Omadacycline (Nuzyra)
Omadacycline was approved in 2018 by the U.S. Food and Drug Administration (FDA) for the treatment of acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP).
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Histoplasmosis — Expansion of Risk Areas and Need for More Standardized Practice
Histoplasmosis is increasingly seen beyond the previous risk areas of the Ohio and Mississippi River valleys. Diagnostic and treatment practices vary widely.
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Vancomycin for MRSA Pneumonia Following Influenza in Children
Coinfection with methicillin-resistant Staphylococcus aureus (MRSA) in children with influenza is associated with high fatality. Data support the addition of a second anti-MRSA antibiotic to vancomycin in severely ill children.
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Is Fecal Microbiota Transplantation Superior to Fidaxomicin for Recurrent Clostridioides difficile Infection?
In a randomized clinical trial, researchers found the combination of oral vancomycin followed by fecal microbiota transplantation was superior to treatment with fidaxomicin or vancomycin alone for patients with recurrent Clostridioides difficile infection.