Infectious Disease Topics
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Possible Aerosol Spread of SARS-CoV-2 in an Apartment Building
Although not definitive, evidence is consistent with aerosol spread of SARS-CoV-2 in an apartment building as a result of transport through the drainage system to apartments directly above.
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A Novel Rifabutin-Containing Combination Regimen Eradicates H. pylori Infection
Researchers found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.
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COVID-19 Vaccine Update
There are dozens of vaccine candidates undergoing investigation in human and animal trials. Only a few have reached Phase III testing. This is a closer look at those.
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Gut Microbiome in Patients at Risk for Parkinson’s Disease
Certain risk factors and prodromal markers of Parkinson’s disease (PD), such as constipation and rapid eye movement sleep behavior disorder, are associated with specific bacterial compositions of the gut. However, the value of gut microbiome data to predict the risk of PD development needs further investigation.
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Antibiotic Use in COVID-19 Patients
Fifty-seven percent of patients with COVID-19 infection treated at 38 hospitals in Michigan received early empiric antibiotics, although researchers documented community-onset bacterial coinfection in only 3.5%.
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HHS Releases Latest Iteration of Antibiotic Resistance Action Plan
The five-point strategy crafted in previous years remains the same, but the tactics have improved to help execute the goals. The new plan includes details about stronger and more evidence-based activities that have reduced antibiotic resistance that public health officials can lean on to drive progress.
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Infectious Disease Alert Updates
Sex in the Time of COVID-19; Serum SARS-CoV-2 and Disease Severity; Natural History of Untreated Tuberculosis
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Gut Microbiome in Patients at Risk for Parkinson’s Disease
Certain risk factors and prodromal markers of Parkinson’s disease (PD), such as constipation and rapid eye movement sleep behavior disorder, are associated with specific bacterial compositions of the gut. However, the value of gut microbiome data to predict the risk of PD development needs further investigation.
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Hospitalized COVID-19 Patients: SARS-CoV-2 RNA in Plasma Associated with ICU Admission and Mortality
A prospective cohort study found that SARS-CoV-2 plasma RNA was detected more often, and the levels were higher, in patients who were admitted to the intensive care unit and/or who died.
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Chronic Low-Dose Corticosteroids and Infection Risk
The prolonged use of low-dose oral corticosteroids (including < 5 mg prednisone equivalent doses) in rheumatoid arthritis patients is associated with an increased risk of infection.