Infectious Disease Topics
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Managing Appendicitis Medically
A multicenter, randomized trial showed that 10 days of antibiotics results in comparable outcomes as surgery. Three in 10 patients treated with antibiotics required surgery within 90 days.
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Ceftriaxone-Resistant Gonorrhea Has Arrived in the United States
A man in Las Vegas with gonorrhea was infected with the first ceftriaxone-resistant strain of Neisseria gonorrhoeae identified in the United States.
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Medical Tourism — Infectious Complications
Infections are a potential complication associated with medical tourism — something that both patients and clinicians must consider.
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Childhood Diseases Associated with Antibiotic Exposure During Infancy
A population-based cohort study showed that exposure to antibiotics during the first two years of life is associated with increased rates of subsequently developing asthma, allergic rhinitis, atopic dermatitis, attention deficit hyperactivity disorder, celiac disease, and obesity.
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Elevated Procalcitonin Is Associated with Increased Mortality in Pulmonary Tuberculosis
A single-center, prospective, observational study found that an elevated procalcitonin level was associated with an increased risk of death in patients with pulmonary tuberculosis.
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Duration of Viable SARS-CoV-2 Shedding in Immunocompromised COVID-19 Patients
Significantly immunocompromised patients with COVID-19 may shed cultivatable virus for as long as two months or more after symptom onset.
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Treatment of COVID-19 Patients with Remdesivir, Hydroxychloroquine, Lopinavir, or Interferon Beta-1a
None of the four drugs studied was superior to placebo.
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Casirivimab + Imdevimab Injection
Casirivimab/imdevimab should be used to treat mild to moderate COVID-19 in adults and patients ≥ 12 years of age weighing at least 40 kg who have tested positive for SARS-CoV-2.
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Antibiotics for Traveler’s Diarrhea
International travel carries a risk of colonization by antimicrobial-resistant intestinal flora. Using quinolone, but not a macrolide, during travel further increases the risk of acquisition of extended-spectrum, beta-lactamase-producing Enterobacteriaceae.
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Healthcare Personnel COVID-19 Hospitalizations and Vaccine Prioritization
During the period of study, 5.9% of individuals hospitalized for COVID-19-related reasons were healthcare providers (HCP), with approximately one-third involving HCP who were not expected to directly contact patients.