Infectious Disease Topics
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Cabotegravir Extended-Release and Rilpivirine Injectable Suspension (Cabenuva) and Cabotegravir Tablets (Vocabria)
Cabotegravir/rilpivirine (CAB/RPV) should be prescribed to treat HIV-1-infected adults. This combination should replace the current antiretroviral (ARV) regimen in those who are virologically suppressed (HIV-1 RNA < 50 copies/mL) on a stable regimen with no history of treatment failure and no known or suspected resistance to ether CAB or RPV.
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Subclinical Influenza Infection in Healthcare Workers
Despite all precautions, influenza vaccination, handwashing campaigns, and messaging to staff not to come to work with respiratory symptoms, healthcare workers are an important source of nosocomial influenza and respiratory infection. Now, it is happening with COVID-19.
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Excess Deaths During COVID-19
Compared with death data for the same weeks from prior years, nearly 300,000 excess deaths occurred in the United States between the weeks ending Jan. 26 through Oct. 3, 2020. Two-thirds were attributed to COVID-19.
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Prior Metformin Use in Patients with Diabetes Hospitalized for COVID-19
Investigators found metformin use before COVID-19 hospitalization for patients with diabetes was associated with a lower risk of death.
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Feds Redefine Who Can Handle COVID-19 Vaccine
HHS expands list of who can prescribe, dispense, and administer shots.
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Does MRSA Nares Colonization Predict Non-Respiratory MRSA Infections?
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) carried a high negative predictive value to rule out MRSA infections at various sites.
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Streamlined Lyme Disease Guidelines for Frontline Providers
With the peak period for Lyme disease approaching, new guidelines help clinicians understand when to consider the ailment in patients who present to the ED, how to properly diagnosis a case, and how to treat.
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Infectious Disease Alert Updates
Excess Deaths During COVID-19; Subclinical Influenza Infection in Healthcare Workers; Compression Garments Effective in Reducing Cellulitis
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Neurotropism of COVID-19: What Is New?
SARS-CoV-2 may gain access to the brain via the olfactory epithelium. The olfactory epithelium and bulbs may serve as an entry point for SARS-CoV-2 infection into the central nervous system.
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Does the Addition of IV Metronidazole Improve Outcomes of Severe Clostridioides difficile Infection?
These studies indicate that the addition of intravenously administered metronidazole in the treatment of severe Clostridioides difficile infection is unwarranted.