-
A randomized, double-blind, placebo-controlled clinical trial of adults aged 18 years and older found that adjunctive daptomycin did not shorten the duration of methicillin-susceptible Staphylococcus aureus bacteremia compared to monotherapy with an antistaphylococcal beta-lactam antibiotic.
-
The need for hospitalization because of COVID-19 is significantly less in adolescents than in older age groups, but nearly one-third of those hospitalized require intensive care unit admission.
-
Party Affiliation and Social Distancing; Ethnicity and Occupation as Risk Factors for COVID Infection
-
Cytomegalovirus (CMV) viremia emerges in the majority of CMV seronegative recipients of liver transplants from CMV seropositive donors, most often within the first post-transplant month. The only independent risk factor identified was increasing donor age.
-
A review of 24 cases of Nocardia brain abscess, two-fifths of which occurred in apparently non-immunocompromised hosts, had variable outcomes, but antibiotic therapy was effective in most.
-
In addition to identifying several patient risk factors for contamination of blood culture specimens, the authors also highlighted various adverse clinical and financial adverse effects.
-
In the United States, rapid diagnostic testing for panels of potential gastrointestinal pathogens in children increases the yield of identifying rare pathogens, but, overall, does not change length of stay for hospitalized patients or reduce hospital charges.
-
In a retrospective study, the investigators failed to find evidence of benefit of adjunctive rifampin therapy in patients with staphylococcal prosthetic valve endocarditis.
-
In elderly patients with bacteremic urinary tract infection (UTI), symptoms of UTI were present in only one-third of patients, only four-fifths had fever, and just three-fifths had an early diagnosis of UTI.
-
A cohort study from the U.S. Department of Veterans Affairs found many survivors of COVID-19 had significant loss of health six months after their acute illness, with greater risk associated with severity of the acute infection.
