Infectious Disease Topics
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Bivalent COVID-19 Vaccine (Booster Dose)
The FDA has amended the emergency use authorizations of two leading COVID-19 vaccines. Now, these new bivalent formulations can be used as a single booster dose (after primary or booster vaccination).
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Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD
This multicenter cohort study revealed a high incidence of PTSD symptoms among family members of COVID-19 patients at three months after the ICU admission.
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Remaining Questions in Syphilis Treatment
Eight leading experts on sexually transmitted diseases convened to discuss key questions in the management of syphilis in adults with and without HIV infection based on a systematic review of the literature. More than 3,000 articles were screened, and the discussion focused on 95 relevant publications and three main topics.
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Cirrhosis and Infections
Infections in patients with cirrhosis are frequent and potentially lethal, with pneumonia associated with the highest risk for mortality.
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COVID-19 and Headache
Headache is a common feature of acute COVID-19 infection, as well as a long-standing feature of “long COVID” after recovery from the acute infection. Treatment is symptomatic, based on the characteristics of the headache syndrome.
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COVID-19: Duration of Shedding of Transmissible Virus
Patients with COVID-19 were found, by culture, to shed replication-competent virus after an initial positive polymerase chain reaction test for median durations four to five days.
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Ethics Consults During Pandemic Inform Preparation for Future Crises
Lessons learned on ethics consults during the COVID-19 pandemic carry important implications for future disasters.
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Delaying Antibiotics in Patients with Suspected Infection Increases Risk of Septic Shock
A retrospective cohort study found that delaying the first dose of antibiotics in patients suspected of having an infection in the emergency department led to a higher risk of progressing to septic shock and in-hospital mortality. Every hour antibiotics were delayed increased the risk of septic shock by 4%.
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Infectious Disease Alert Updates
Mandating COVID-19 Vaccination for Healthcare Workers — Revisited; SARS-CoV-2 as a North American Zoonosis; VIRSTA vs. PREDICT in Predicting Endocarditis
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Herpes Simplex Virus 2 Meningitis in Adults
The incidence of herpes simplex virus 2 meningitis in adults in Denmark over a six-year period was 0.7/100,000 population per year, with 91% of cases occurring in the absence of immunocompromise. Neurocognitive or neuropsychiatric symptoms persisted for as long as six months in approximately one-fifth of cases.