Infectious Disease Topics
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Concerns and Complications of Measles and Mumps
Decreased vaccine coverage against diseases such as measles and mumps has led to new vulnerabilities in pediatric population health. Thus, the astute practitioner should be vigilant and ready to recognize and diagnose these infections.
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Resistance of SARS-CoV-2 Variants to Monoclonal Antibodies
Prevalent SARS-CoV-2 variants are persistently resistant to therapeutic and prophylactic monoclonal antibodies but remain susceptible to nirmatrelvir/ritonavir, remdesivir, and molnupiravir.
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Vaccination Against Mpox: Does It Work? Is It Safe?
Vaccination, either subcutaneously or intradermally, with the non-replicating Jynneos monkeypox vaccine is safe and effective.
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Physician Autonomy at Issue if Patients Demand Ineffective Treatments
A controversial Wisconsin Supreme Court case centers on whether physicians can be legally required to provide ivermectin for COVID-19 if a patient or family requests it.
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Tocilizumab Injection (Actemra)
The FDA has approved tocilizumab injection to treat COVID-19 among hospitalized adult patients who are receiving systemic corticosteroids and require supplemental oxygen.
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COVID-19: Beware Remdesivir Resistance
Researchers reported two immunosuppressed renal transplant recipients with persistent SARS-CoV-2 infection in association with the new emergence of mutations in RNA-dependent RNA polymerase after remdesivir treatment.
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Fecal Microbiota, live-jslm (Rebyota)
Rebyota can be prescribed to prevent recurring Clostridioides difficile infection for patients age 18 years and older who are following antibiotic treatment for recurring episodes.
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It’s Not All About the Cough
Be careful about relying on clinical queries that focus on the presence of cough for two or more weeks, which could lead to delays in the diagnosis of nearly half of pulmonary tuberculosis cases.
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Ethical Justification for Research on Dangerous Pathogens
Recent inflammatory headlines suggested researchers had created a more dangerous version of COVID. However, those researchers said the headlines were misleading. Nevertheless, it spotlighted the ethical concerns involving research on pathogens.
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WHO Lobbies for Updated Tuberculosis Vaccines
International organization says these investments could drive economic growth, improve health equity and antimicrobial stewardship, and lower mortality rates.