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Balb/CJ mice infected with influenza virus were superinfected with an antibiotic-susceptible strain of S. pneumoniae and treated intraperitoneally with ampicillin alone, clindamycin alone, ampicillin plus clindamycin, or azithromycin.
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Patients with lyme arthritis were more likely to have knee involvement (p < 0.001), a history of a tick bite (p = 0.02), and less likely to have a history of fever (p < 0.001) or fever ...
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In this issue: Aspirin dose and cardioprotection; uncovering modafinil's abuse potential; proton-pump inhibitors and clopidogrel; FDA actions.
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Much is being written about the transmission of MRSA between animals and humans. These investigators explored this problem from another angle, examining colonization of pet therapy dogs with MRSA, VRE, and C. difficile during visits to acute and long-term care facilities.
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Extended spectrum β-lactamase (ESBL)-producing Escherichia coli has emerged as an increasingly common cause of community-acquired urinary tract infections (UTIs).
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These guidelines were last updated for adults in 2002 and for adolescents in 2004. The document (available in pdf format through the link above) is a 209-page file containing 1,391 references which update current recommendations for the prophylaxis and treatment of HIV-related OIs.
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In vitro treatment of clinical isolates and isogenic strains of E. coli O157:H7 with ciprofloxacin increased the production of Stx2 (as measured by ELISA) via phage induction but did not increase the production of Stx1.
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In this issue: Individualization of therapy with pharmacogenetics; the rate vs rhythm debate; the FDA's Risk Evaluation and Mitigation Strategy; FDA actions.
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Faced with limited data about acute mountain sickness in children who travelled rapidly to high altitudes, Swiss researchers studied symptoms in 48 children (ages 10-17, mean age 13) who traveled 2.5 hours from low altitude (568 meters) to 3,450 meters (approximately 11,200 feet).