Infectious Disease Alert
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Autochthonous Crimean-Congo Hemorrhagic Fever in Europe
Two patients with Crimean-Congo hemorrhagic fever acquired in Spain are reported. The index patient acquired infection from a tick bite, and the second patient was a nurse who cared for the index patient. The first patient died in the hospital with multi-system organ failure and was diagnosed at autopsy. The second patient recovered with supportive care and was treated with ribavirin, but it was unclear whether the use of ribavirin was helpful.
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Microbiology of Hidradenitis Suppurativa: New Evidence That Anaerobes Predominate
Using metagenomic techniques, investigators determined that two Gram-negative anaerobes, Prevotella and Porphyromonas, predominate in hidradenitis suppurativa lesions. Two others, Fusobacterium and Parvimonas, correlate with disease severity.
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CDC Update of Notifiable Infectious Diseases
CDC has updated the available information regarding reportable infectious diseases in the United States.
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Infectious Disease Alert Updates
How Dirty Is That Sandbox?; Rebuilding the Pyramids; Resistant TB in India: Unrecognized Mutations
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GASP! Increasing Worldwide Antibiotic Resistance in Neisseria gonorrhoeae
Antibiotic-resistant gonorrhea threatens to make the infection untreatable in some patients.
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Azithromycin for Chronic Persistent Asthma
Azithromycin reduced exacerbations and improved quality of life in patients with chronic persistent asthma.
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Tetracycline for Multiple Sclerosis?
One hundred forty-two patients within 180 days of their first demyelinating event were randomized to minocycline 100 mg BID vs. placebo. The unadjusted risk of conversion to multiple sclerosis within six months after randomization was 61.0% in the placebo group and 33.4% in the minocycline group. At 24 months, the effect of minocycline was not statistically significant.
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Cefazolin Leads to Better Outcomes for Methicillin-susceptible Staphylococcus aureus Bacteremia Than Nafcillin or Oxacillin
A retrospective study that included patients from 119 Veterans Affairs hospitals found lower mortality and a similar recurrence rate for methicillin-susceptible Staphylococcus aureus bacteremia treated with cefazolin compared to nafcillin and oxacillin.
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Neonatal Group B Streptococcal Bacteremia Associated With Placentophagy
Associated with a mother’s ingestion of encapsulated placenta, an otherwise healthy newborn developed and, with antimicrobial treatment, recovered from both early and late onset group B streptococcal bacteremia. This is apparently the first report of a serious negative consequence of maternal consumption of dried placenta.