Infectious Disease Alert
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Infectious Disease Alert Updates
Utility of GI Multiplex Assay; ‘The World Is Covered by a Thin Layer of Feces’
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Why IDSA Did Not Support the Surviving Sepsis Campaign
The Infectious Diseases Society of America withheld its support for the Surviving Sepsis guidelines. The general concerns included vagueness and inconsistency in definition of sepsis, “one size fits all” prescription of time to administer antibiotics, lack of clarity around drawing blood cultures through IV catheters, recommendation of combination antibiotics, lack of definition around when to use procalcitonin levels, when and how to use pharmacokinetic and pharmacodynamic data effectively, prolonged antibiotic “prophylaxis,” and duration of therapy.
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Oral Antibiotics May Increase the Risk for Nephrolithiasis
A case-control study found that receipt of an oral antibiotic in the preceding three to 12 months was associated with nephrolithiasis. The risk persisted up to five years, and younger patients were at increased risk.
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Reduced Noninfectious Adverse Events After Discontinuation of Contact Precautions in Patients Colonized or Infected With MRSA and/or VRE
Discontinuation of contact precautions for patients colonized or infected with either MRSA or VRE is associated with a decrease in rates of noninfectious adverse events.
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VRE and MRSA: Time to Assign Contact Precautions to the Dust Heap of History
In the context of other horizontally implemented, effective infection prevention measures, the use of contact precautions for most patients colonized or infected with MRSA or VRE fails to provide benefit.
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Rotavirus Vaccine and Intussusception
Using active surveillance, researchers enrolled 717 infants with intussusception from sub-Saharan Africa. The risk of intussusception was no higher in those who received the monovalent rotavirus vaccine than in non-immunized infants.
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Antibiotic Use in Infancy Associated With Allergic Disease During Childhood
In a large population-based study, antibiotic use during the first six months of life was associated with a two-fold increase in asthma and a 1.5-fold increase in allergic disease during early childhood.
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Infectious Disease Alert Updates
House Mice as Vectors; Eat Your Fruits and Vegetables — or You Might Get TB!
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Another Reason to Get the Flu Shot Every Year
In a case-control study, among older adults, repeated vaccination for influenza was twice as effective in preventing severe influenza compared to non-severe influenza in patients who were admitted to the hospital.
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Fosfomycin or Nitrofurantoin for Cystitis?
A single dose of fosfomycin was found to be less effective than five days of thrice-daily dosing of nitrofurantoin in the treatment of symptomatic lower urinary tract infection in women.