Infectious Disease Alert
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Biofilm, Tap Water, and a Nosocomial Mycobacterium abscessus Outbreak — Bring on the Sterile Water
Stopping a nosocomial Mycobacterium abscessus outbreak by eschewing tap water.
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Possible Aerosol Spread of SARS-CoV-2 in an Apartment Building
Although not definitive, evidence is consistent with aerosol spread of SARS-CoV-2 in an apartment building as a result of transport through the drainage system to apartments directly above.
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Four Months of Rifampin Is Just as Effective, Safer, and Less Expensive than Nine Months of Isoniazid for Latent Tuberculosis
A health system cost comparison found that four months of rifampin was safer and less expensive than nine months of isoniazid in high-income countries, medium-income countries, and African countries.
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Antibiotic Use in COVID-19 Patients
Fifty-seven percent of patients with COVID-19 infection treated at 38 hospitals in Michigan received early empiric antibiotics, although only 3.5% of patients had documented community-onset bacterial co-infection.
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Seasonal Coronavirus: A “Common Cold Virus” that May Be Lethal in Severely Immunocompromised Patients
Seasonal coronaviruses, which are a frequent cause of benign upper respiratory tract infections, may be fatal in severely immunocompromised patients.
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Repeat SARS-CoV-2 Infection
Whole genome sequencing confirmed that repeat infection with SARS-CoV-2 is possible, something that has consequences for vaccine use and for public health.
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Infectious Disease Alert Updates
Things Do Not Always Go Better with Cola; ‘Hygiene Theater’; Geodynamics of COVID-19 in Brazil
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Respiratory Syncytial Virus — Not Just a Disease of Children
Respiratory syncytial virus is a significant cause of morbidity and mortality in the elderly.
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A Novel Rifabutin-Containing Combination Regimen Is Effective for Eradicating H. pylori Infection
A Phase III, randomized, controlled trial found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.
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Respiratory Syncytial Virus — Effective Prevention Still Needed
Prevention of respiratory syncytial virus infection is needed but challenging. New studies show some favorable effectiveness on infant outcomes with both vaccination of healthy pregnant women and passive single-dose immunization of prematurely born babies.