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In a survey of 365,000 records of patients followed by general practitioners in Holland for at least 1 year during a 7-year period, 5551 incident cases of pneumonia developed. Users of acid suppression, particularly proton pump inhibitors (PPIs), had a 4.5 fold increased unadjusted risk of pneumonia, compared to untreated controls.
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Wild poliovirus (WPV) was imported into 8 countries that were previously felt to be polio-free in west Africa (Benin, Burkina Faso, Cote dIvoire, Ghana, Togo) and Central Africa (Cameroon, Central African Republic, Chad) from January 2003 to March 2004.
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The Centers for Disease Control (CDC) has confirmed the diagnosis of rabies in 4 recipients of transplanted organs and their common donor. All 4 transplant recipients presented with rapidly progressive encephalitis within 21 to 27 days after receiving their transplant and all subsequently died.
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Dial and colleagues point out that Clostridium difficile is the most common form of nosocomial infectious diarrhea in the Western world, apparently increasing in frequency, severity, and consequential health care costs (more than $1 billion in the United States annually).
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All 165 cases of malaria-related deaths in the United States reported to the National Malaria Surveillance System from 1963 to 2001 were reviewed. Two-thirds occurred in US travelers, and 92.7% of deaths were due to Plasmodium falciparum infection.
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A retrospective review found evidence indicating improved survival when voriconazole was used in combination with caspofungin than when voriconazole was used alone in the treatment of patients with invasive aspergillos failing therapy with amphotericin B.
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Over a 7-year period, there was a dramatic increase in the isolation of community-acquired MRSA in the San Francisco area. Molecular typing showed movement of community-acquired strains into hospitals.
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Flu ShortageWho Cares?; Can Cutaneous Zoster Result in Airborne Transmission?; If It Was a Bear. . . Part II; Breakthrough Fungal Infection With Voriconazole.