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Of 583 children < 18 years of age tested for anti-neutrophil cytoplasmic antibody (ANCA) at Boston Children's Hospital from 1996 to 2006, 27 children had a history of minocycline administration, with clinical and laboratory findings of autoimmunity. Of these 27 children, 19 were female (70%).
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A retrospective study of all 5,817 neonates (¡Ü 28 days of age) admitted from the Emergency Department to Texas Children's Hospital from 2001 through 2005 found that 8.6% (95% CI, 7.9-9.3%) had documented viral infections (8.4% non-HSV and 0.2% HSV), and 4.6% (95% CI, 4.1-5.2%) had documented serious bacterial infections.
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Chagas disease (American Trypanosomiasis) is caused by infection with the protozoan parasite Trypanosoma cruzi, and is spread primarily by triatomine insect vectors ("kissing bugs").
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Resistance to oseltamivir (tamifluR) has increased in Influenza A isolates around the world at an alarming rate. Levels of resistance now range from 13% in Chile to 100% (10 of 10 isolates) in Australia.
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Investigators at a number of university-affiliated HIV clinics around the United States conducted the Living Positively Survey to explore the experiences and attitudes of HIV+ woman toward health care, treatment, pregnancy, and family issues.
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Although reactivation of CMV has significant adverse consequences for immunocompromised patients, such as those receiving organ transplants, the effect of CMV reactivation in critically ill immunocompetent patients is unclear.
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In this issue: Some women with DVT may stop warfarin after six months; Vytorin and cancer; preventing recurrent stroke; and FDA news.
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Patients with burn injuries are at high risk for major infections, given their impaired humoral and cellular immunity. Moreover, this patient population displays numerous physiologic alterations affecting organ function and drug metabolism.
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The yearly update of recommendations for prevention and control of influenza is available. There have been only few changes from last year. The following focuses on areas of particular interest, including those which seem to generate the most questions. Changes for this year are indicated by their italicization.