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Amoxicillin-Clavulanate vs Ciprofloxacin; AD Therapy and Cognitive Function; LDL Lowering in CHD Patients; FDA Actions
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Palifermin, a recombinant form of human keratinocyte growth factor, reduced the duration and severity of oral mucositis and the incidence of febrile neutropenia and bacteremia among patients given intensive chemotherapy and radiotherapy for hematologic cancers.
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HHV6 infection occurred primarily during the first 2 years of life. Most infections were symptomatic, but with nonspecific symptoms. Among 81 children with well-defined time of infection, roseola occurred in only 23%. None of these children had febrile seizures.
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The potential for a clinically detrimental interaction between didanosine and tenofovir disoproxil fumarate (DF) has received considerable attention lately in the medical community. Tenofovir DF is a nucleotide analog of adenosine 5-monophosphate, which was approved by the Food and Drug Administration (FDA) for the treatment of human immunodeficiency virus (HIV) infection in October 2001. Didanosine, 1 of 7 nucleoside reverse transcriptase inhibitors (NRTIs) marketed in the United States, has been implicated as the causative agent significant adverse events such as lactic acidosis/hepatic steatosis, pancreatitis, and peripheral neuropathy.
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A multicenter study of 4 non-invasive tests for Helicobacter pylori infection in children and adolescents showed the urea breath test to be the preferred diagnostic test, with the greatest sensitivity among all age groups.
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On February 11, 2005 the New York City Department of Health sent out a Dear Colleague letter reporting the case of a homosexual man who sustained primary infection with a 3-drug-class-resistant HIV-1 accompanied by rapid CD4+ T cell depletion and progression to AIDS.
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Amazing Teen Survives Rabies; India, Genetics, and HIV; Illicit Botox Products; Sharing Your MRSA With Your Pet; Could Sepsis Respond to Nicotine?
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The FDA has issued a public Health Advisory regarding the identification of 4 cases of toxic shock following medical abortion with Mifepristone (formerly RU-486) and intravaginal misoprostol in the United States.
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The FDA has recently approved daptomycin for use in skin and skin-structure infections, but this antibiotic failed the test of non-inferiority in a trial of severe community-acquired pneumonia.
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Saccharomyces boulardii (recently recognized as a strain of S. cerevisiae rather than a distinct species) is widely used as a probiotic for the treatment of diarrhea and for the prevention and treatment of C. difficile-associated colitis.