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The risk of venous thromboembolism was double in users of a transdermal contraceptive as compared to users of an oral contraceptive with a 35 mcg ethinyl estradiol component. Warning: no abstract skimming — it's worth your while to keep reading!
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This multi-center, randomized, double-blind clinical trial demonstrated that the addition of vasopressin to patients receiving norepinephrine for management of septic shock had no effect on mortality when compared to increasing the norepinephrine dose.
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Intravascular volume expansion has long been advised as an effective temporizing technique for patients with cardiac tamponade prior to drainage of the fluid, but there is little data supporting this practice.
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Vernakalant is a new investigational anti-arrhythmic drug. The compound is relatively selective, blocking the early-activating potassium channel and the frequency-dependent sodium channel; it has a half-life of two to three hours.
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Pioglitazone and heart disease; ARBs manufacturers spend millions to show the non-inferiority of their products compared to less expensive, generic ACE inhibitors; some athletes turn to growth hormone because it is difficult to detect; FDA Actions
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A multicenter, randomized, double-blind, placebo-controlled trial of hydrocortisone replacement in patients with septic shock found no mortality benefit in those patients with inadequate baseline response to corticotropin stimulation.
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There is an increased risk of future cancer as a consequence of performing repeated CT scans, and the younger the patient at the time of scanning, the greater the subsequent risk.
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Exposure to small turtles has lead to a multistate outbreak of Salmonella paratyphi B var. Java infections. This MMWR report summarizes the epidemiologic and laboratory investigation conducted by CDC and state and local health departments since the first reported illness on 5/4/07.
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Risk prediction algorithms for non-cardiac surgery and therapeutic trials have focused on the prevention of myocardial ischemic events.
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This study of severe sepsis patients showed that intensive insulin therapy does not improve mortality or organ dysfunction, and resuscitating patients with the colloid hydroxyethyl starch is harmful.
